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Difference between revisions of "Acquired cystic disease-associated renal cell carcinoma"
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Acquired cystic disease-associated renal cell carcinoma (view source)
Revision as of 23:37, 26 May 2018
, 23:37, 26 May 2018oxylate -> oxalate
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| Caption = Acquired cystic disease-associated renal cell carcinoma. [[H&E stain]]. | | Caption = Acquired cystic disease-associated renal cell carcinoma. [[H&E stain]]. | ||
| Synonyms = | | Synonyms = | ||
| Micro = sieve-like architecture (tubular structures/cribriforming), tumour cells with prominent nucleoli and eosinophilic cytoplasm, | | Micro = sieve-like architecture (tubular structures/cribriforming), tumour cells with prominent nucleoli and eosinophilic cytoplasm, oxalate crystals - seen best in [[polarized light]], acquired cystic disease in background, +/-papillary structures - common minor component | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[acquired cystic renal disease]], [[papillary renal cell carcinoma]], [[hereditary leiomyomatosis renal cell carcinoma syndrome associated renal cell carcinoma]] | | LMDDx = [[acquired cystic renal disease]], [[papillary renal cell carcinoma]], [[hereditary leiomyomatosis renal cell carcinoma syndrome associated renal cell carcinoma]] | ||
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**Focal papillary architecture - common.<ref name=pmid16434887>{{Cite journal | last1 = Tickoo | first1 = SK. | last2 = dePeralta-Venturina | first2 = MN. | last3 = Harik | first3 = LR. | last4 = Worcester | first4 = HD. | last5 = Salama | first5 = ME. | last6 = Young | first6 = AN. | last7 = Moch | first7 = H. | last8 = Amin | first8 = MB. | title = Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia. | journal = Am J Surg Pathol | volume = 30 | issue = 2 | pages = 141-53 | month = Feb | year = 2006 | doi = | PMID = 16434887 }}</ref> | **Focal papillary architecture - common.<ref name=pmid16434887>{{Cite journal | last1 = Tickoo | first1 = SK. | last2 = dePeralta-Venturina | first2 = MN. | last3 = Harik | first3 = LR. | last4 = Worcester | first4 = HD. | last5 = Salama | first5 = ME. | last6 = Young | first6 = AN. | last7 = Moch | first7 = H. | last8 = Amin | first8 = MB. | title = Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia. | journal = Am J Surg Pathol | volume = 30 | issue = 2 | pages = 141-53 | month = Feb | year = 2006 | doi = | PMID = 16434887 }}</ref> | ||
**Tumour cells have prominent nucleoli ([[ISUP nucleolar grade]] 3) and eosinophilic cytoplasm. | **Tumour cells have prominent nucleoli ([[ISUP nucleolar grade]] 3) and eosinophilic cytoplasm. | ||
* | *Oxalate crystals - '''important'''. | ||
**Look somewhat like cholesterol clefts. | **Look somewhat like cholesterol clefts. | ||
**Seen easily in [[polarized light]]. | **Seen easily in [[polarized light]]. | ||