Difference between revisions of "TFE3"

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'''TFE3''' is an [[immunostain]] used in [[uropathology]] and [[soft tissue pathology]].
'''TFE3''' is an [[immunostain]] used in [[uropathology]] and [[soft tissue pathology]].
The reliability of the immunostain for detecting TFE3 rearrangments has been questioned by at least one study.<ref name=pmid30851332>{{cite journal |vauthors=Sharain RF, Gown AM, Greipp PT, Folpe AL |title=Immunohistochemistry for TFE3 lacks specificity and sensitivity in the diagnosis of TFE3-rearranged neoplasms: a comparative, 2-laboratory study |journal=Hum Pathol |volume=87 |issue= |pages=65–74 |date=May 2019 |pmid=30851332 |doi=10.1016/j.humpath.2019.02.008 |url=}}</ref>


==Negative==
==Negative==
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*[[Xp11.2 translocation carcinoma]].
*[[Xp11.2 translocation carcinoma]].
*[[Alveolar soft part sarcoma]].
*[[Alveolar soft part sarcoma]].
* YAP-TFE3 translocated [[epithelioid hemangioendothelioma]]
*[[Epithelioid angiomyolipoma]].
*[[Granular cell tumour]].<ref>{{cite journal |authors=Chamberlain BK, McClain CM, Gonzalez RS, Coffin CM, Cates JM |title=Alveolar soft part sarcoma and granular cell tumor: an immunohistochemical comparison study |journal=Hum. Pathol. |volume=45 |issue=5 |pages=1039–44 |date=May 2014 |pmid=24746209 |doi=10.1016/j.humpath.2013.12.021 |url=}}</ref>


==See also==
==See also==
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