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Difference between revisions of "Lupus erythematosus cell"
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'''Lupus erythematosus cell''', abbreviated ''LE cell'', is [[neutrophil]] that has engulfed an intact nucleus.<ref name=pmid26118732>{{Cite journal | last1 = Magna | first1 = M. | last2 = Pisetsky | first2 = DS. | title = The Role of Cell Death in the Pathogenesis of SLE: Is Pyroptosis the Missing Link? | journal = Scand J Immunol | volume = 82 | issue = 3 | pages = 218-24 | month = Sep | year = 2015 | doi = 10.1111/sji.12335 | PMID = 26118732 }}</ref> This is seen in [[systemic lupus erythematosus]]. | '''Lupus erythematosus cell''', abbreviated ''LE cell'', is [[neutrophil]] that has engulfed an intact nucleus.<ref name=pmid26118732>{{Cite journal | last1 = Magna | first1 = M. | last2 = Pisetsky | first2 = DS. | title = The Role of Cell Death in the Pathogenesis of SLE: Is Pyroptosis the Missing Link? | journal = Scand J Immunol | volume = 82 | issue = 3 | pages = 218-24 | month = Sep | year = 2015 | doi = 10.1111/sji.12335 | PMID = 26118732 }}</ref> This is seen in [[systemic lupus erythematosus]]. | ||
It is also known as a '''LE body'''. | |||
==General== | |||
*Initially described in [[bone marrow]].<ref>{{Cite journal | last1 = HARGRAVES | first1 = MM. | last2 = RICHMOND | first2 = H. | last3 = MORTON | first3 = R. | title = Presentation of two bone marrow elements; the tart cell and the L.E. cell. | journal = Proc Staff Meet Mayo Clin | volume = 23 | issue = 2 | pages = 25-8 | month = Jan | year = 1948 | doi = | PMID = 18921142 }}</ref> | *Initially described in [[bone marrow]].<ref name=pmid18921142>{{Cite journal | last1 = HARGRAVES | first1 = MM. | last2 = RICHMOND | first2 = H. | last3 = MORTON | first3 = R. | title = Presentation of two bone marrow elements; the tart cell and the L.E. cell. | journal = Proc Staff Meet Mayo Clin | volume = 23 | issue = 2 | pages = 25-8 | month = Jan | year = 1948 | doi = | PMID = 18921142 }}</ref> | ||
==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid26118732/> | Features:<ref name=pmid26118732/> | ||
*Neutrophil that has engulfed a blue body on H&E. | *Neutrophil that has engulfed a round blue body on H&E. | ||
==See also== | ==See also== | ||