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*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285085/figure/F1/ Mimics of GB carcinoma (nih.gov)].<ref name=pmid22284391>{{Cite journal | last1 = Giang | first1 = TH. | last2 = Ngoc | first2 = TT. | last3 = Hassell | first3 = LA. | title = Carcinoma involving the gallbladder: a retrospective review of 23 cases - pitfalls in diagnosis of gallbladder carcinoma. | journal = Diagn Pathol | volume = 7 | issue = | pages = 10 | month = | year = 2012 | doi = 10.1186/1746-1596-7-10 | PMID = 22284391 }}</ref> | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285085/figure/F1/ Mimics of GB carcinoma (nih.gov)].<ref name=pmid22284391>{{Cite journal | last1 = Giang | first1 = TH. | last2 = Ngoc | first2 = TT. | last3 = Hassell | first3 = LA. | title = Carcinoma involving the gallbladder: a retrospective review of 23 cases - pitfalls in diagnosis of gallbladder carcinoma. | journal = Diagn Pathol | volume = 7 | issue = | pages = 10 | month = | year = 2012 | doi = 10.1186/1746-1596-7-10 | PMID = 22284391 }}</ref> | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285085/figure/F2/ Dysplasia in RA sinuses (nih.gov)]. | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285085/figure/F2/ Dysplasia in RA sinuses (nih.gov)]. | ||
[[File:5 42027008799505 sl 1.png| Moderately differentiated adenocarcinoma of gallbladder]] | |||
[[File:5 42027008799505 sl 2.png| Moderately differentiated adenocarcinoma of gallbladder]] | |||
[[File:5 42027008799505 sl 3.png| Moderately differentiated adenocarcinoma of gallbladder]] | |||
[[File:5 42027008799505 sl 4.png| Moderately differentiated adenocarcinoma of gallbladder]] | |||
[[File:5 42027008799505 sl 5.png| Moderately differentiated adenocarcinoma of gallbladder]] | |||
[[File:5 42027008799505 sl 6.png| Moderately differentiated adenocarcinoma of gallbladder]]<br> | |||
Moderately differentiated adenocarcinoma of gallbladder in a 59 year old man. A. Tumor bounds cystic duct. B. Cystic duct at left shows high grade dysplasia. At right lie acini and nests of round and sometimes spindled cancerous nuclei. Overall most of the tumor was in tubules/acini, meaning the lesion is moderately differentiated. C. Region with Rokitansky-Aschoff sinuses showing high grade dysplasia and foci of intestinal metaplasia, with some nests likely being invasive cancer. D. Tumorous involvement of cystic duct lymph node. E. Bizarrely shaped cancerous groups. F. invasion of liver by neoplastic acini. | |||
==IHC== | ==IHC== |