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Solitary fibrous tumour (view source)
Revision as of 07:14, 15 December 2016
, 07:14, 15 December 2016reformatted. @Mitchell: Do you have the permission to re-use the images here? Am J Surg Pathol is not OpenAccess by default.
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Jensflorian (talk | contribs) (reformatted. @Mitchell: Do you have the permission to re-use the images here? Am J Surg Pathol is not OpenAccess by default.) |
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*[http://path.upmc.edu/cases/case272.html SFT of the brain - several images (upmc.edu)]. | *[http://path.upmc.edu/cases/case272.html SFT of the brain - several images (upmc.edu)]. | ||
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Malignant solitary fibrous tumor (low to intermediate grade tumor). 15 cm mass in upper arm of 50 year old man.<ref>Am J Surg Pathol 2014;38:552-559</ref> | |||
File:3 18039322534203 sl 1.png|malignant solitary fibrous tumor | Hypocellular (green arrow) and hypercellular (cyan arrow) areas alternate. | |||
[[File:3 18039322534203 sl 4.png|malignant solitary fibrous tumor | File:3 18039322534203 sl 2.png|malignant solitary fibrous tumor | Vascular spaces suggest antlers (staghorn). Note subcapsular hemorrhage. | ||
File:3 18039322534203 sl 3.png|malignant solitary fibrous tumor | Stromal hyalinization | |||
[[File:3 18039322534203 sl 4.png|malignant solitary fibrous tumor | Nuclei, lacking organization, show varied size and shape, with some cells being round to ovoid. The arrow points to myxoid focus in stroma. When a majority of the following are present, a low to intermediate grade malignant solitary fibrous tumor is present: 1) size > 5 cm (this case), 2) pleomorphism with round cells/epithelioid cells (this case), 3) subcapsular hemorrhage (this case), 4) ≥4 mitoses per 10 high power fields, 5) necrosis with perivascular tumor sparing. STAT 6 positivity is very helpful in separating this tumor from its mimics | |||
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==IHC== | ==IHC== | ||