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Difference between revisions of "Endometrial hyperplasia"
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(→Simple endometrial hyperplasia with atypia: split out) |
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The most widely used system is from the World Health Organization (WHO). | The most widely used system is from the World Health Organization (WHO). | ||
===WHO classification - overview=== | ===WHO endometrial hyperplasia classification of 1994 - overview=== | ||
The WHO system is based on determining: | The WHO system of 1994 is based on determining:<ref name=pmid25797956>{{Cite journal | last1 = Emons | first1 = G. | last2 = Beckmann | first2 = MW. | last3 = Schmidt | first3 = D. | last4 = Mallmann | first4 = P. | title = New WHO Classification of Endometrial Hyperplasias. | journal = Geburtshilfe Frauenheilkd | volume = 75 | issue = 2 | pages = 135-136 | month = Feb | year = 2015 | doi = 10.1055/s-0034-1396256 | PMID = 25797956 }}</ref> | ||
# Gland density (normal = ''simple hyperplasia'', high density = ''complex hyperplasia''). | # Gland density (normal = ''simple hyperplasia'', high density = ''complex hyperplasia''). | ||
# Presence/absence of nuclear atypia. | # Presence/absence of nuclear atypia. | ||
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**Progestins + close follow-up ''OR'' hysterectomy. | **Progestins + close follow-up ''OR'' hysterectomy. | ||
===Risk of progression to carcinoma=== | ===Risk of progression to carcinoma as per 1994 system=== | ||
Approximate risk of progression to [[endometrial carcinoma]] - Latta rule of 3s:<ref>Latta, E. January 2009.</ref> | Approximate risk of progression to [[endometrial carcinoma]] - Latta rule of 3s:<ref>Latta, E. January 2009.</ref> | ||
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