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Difference between revisions of "Langerhans cell histiocytosis"
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Langerhans cell histiocytosis (view source)
Revision as of 03:45, 16 March 2011
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Langerhans cells histiocytes | *Langerhans cells histiocytes - '''key feature'''. | ||
**Clusters of cells (histiocytes) with a reniform (kidney-shaped) nucleus and abundant foamy cytoplasm. | **Clusters of cells (histiocytes) with a reniform (kidney-shaped) nucleus and abundant foamy cytoplasm. | ||
***Nucleus may look like a "coffee bean", i.e. have nuclear grooves (similar to those in [[papillary thyroid carcinoma]]) -- appearance dependent on the rotation of the nucleus.<ref>BN. 15 March 2011.</ref> | ***Nucleus may look like a "coffee bean", i.e. have nuclear grooves (similar to those in [[papillary thyroid carcinoma]]) -- appearance dependent on the rotation of the nucleus.<ref>BN. 15 March 2011.</ref> | ||