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'''Amnion nodosum''' is an uncommon benign [[placental pathology]]. | '''Amnion nodosum''' is an uncommon benign [[placental pathology]]. | ||
==General== | |||
*Associated with (long-standing) [[oligohydramnios]].<ref>URL: [http://library.med.utah.edu/WebPath/PLACHTML/PLAC042.html http://library.med.utah.edu/WebPath/PLACHTML/PLAC042.html]. Accessed on: 12 January 2011.</ref> | *Associated with (long-standing) [[oligohydramnios]].<ref>URL: [http://library.med.utah.edu/WebPath/PLACHTML/PLAC042.html http://library.med.utah.edu/WebPath/PLACHTML/PLAC042.html]. Accessed on: 12 January 2011.</ref> | ||
*Should be separated from ''squamous metaplasia of amnion''. | *Should be separated from ''squamous metaplasia of amnion''. | ||
==Gross== | |||
Features:<ref name=pmid18081444>{{Cite journal | last1 = Adeniran | first1 = AJ. | last2 = Stanek | first2 = J. | title = Amnion nodosum revisited: clinicopathologic and placental correlations. | journal = Arch Pathol Lab Med | volume = 131 | issue = 12 | pages = 1829-33 | month = Dec | year = 2007 | doi = 10.1043/1543-2165(2007)131[1829:ANRCAP]2.0.CO;2 | PMID = 18081444 }}</ref> | Features:<ref name=pmid18081444>{{Cite journal | last1 = Adeniran | first1 = AJ. | last2 = Stanek | first2 = J. | title = Amnion nodosum revisited: clinicopathologic and placental correlations. | journal = Arch Pathol Lab Med | volume = 131 | issue = 12 | pages = 1829-33 | month = Dec | year = 2007 | doi = 10.1043/1543-2165(2007)131[1829:ANRCAP]2.0.CO;2 | PMID = 18081444 }}</ref> | ||
*Yellow nodules ~ 1-5 mm. | *Yellow nodules ~ 1-5 mm. | ||
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*[[Squamous metaplasia of the amnion]] - large irregular patches, usu. white. | *[[Squamous metaplasia of the amnion]] - large irregular patches, usu. white. | ||
Images | ===Images=== | ||
*[http://www.webpathology.com/image.asp?n=2&Case=659 Amnion nodosum (webpathology.com)]. | *[http://www.webpathology.com/image.asp?n=2&Case=659 Amnion nodosum (webpathology.com)]. | ||
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-131-12-1829-f01&doi=10.1043%2F1543-2165%282007%29131%5B1829%3AANRCAP%5D2.0.CO%3B2 Amnion nodosum & squamous metaplasia of the amnion (archivesofpathology.org)].<ref name=pmid18081444/> | *[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-131-12-1829-f01&doi=10.1043%2F1543-2165%282007%29131%5B1829%3AANRCAP%5D2.0.CO%3B2 Amnion nodosum & squamous metaplasia of the amnion (archivesofpathology.org)].<ref name=pmid18081444/> | ||
<!-- annoying use of '[' and ']' - had to go find escape characters here: http://www.w3schools.com/tags/ref_urlencode.asp --> | <!-- annoying use of '[' and ']' - had to go find escape characters here: http://www.w3schools.com/tags/ref_urlencode.asp --> | ||
==Microscopic== | |||
Features:<ref name=pmid18081444/> | Features:<ref name=pmid18081444/> | ||
*Stratified squamous epithelium - non-keratinizing ''or'' minimal keratin. | *Stratified squamous epithelium - non-keratinizing ''or'' minimal keratin. | ||
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*Normal amnion = simple epithelium. | *Normal amnion = simple epithelium. | ||
Images | ===Images=== | ||
*[http://www.webpathology.com/image.asp?case=659&n=3 Amnion nodosum (webpathology.com)]. | *[http://www.webpathology.com/image.asp?case=659&n=3 Amnion nodosum (webpathology.com)]. | ||
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-131-12-1829-f01&doi=10.1043%2F1543-2165%282007%29131%5B1829%3AANRCAP%5D2.0.CO%3B2 Amnion nodosum & squamous metaplasia of the amnion (archivesofpathology.org)].<ref name=pmid18081444/> | *[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-131-12-1829-f01&doi=10.1043%2F1543-2165%282007%29131%5B1829%3AANRCAP%5D2.0.CO%3B2 Amnion nodosum & squamous metaplasia of the amnion (archivesofpathology.org)].<ref name=pmid18081444/> |
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