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Difference between revisions of "Amnion nodosum"
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'''Amnion nodosum''' is an uncommon benign [[placental pathology]]. | |||
===General=== | |||
*Associated with (long-standing) [[oligohydramnios]].<ref>URL: [http://library.med.utah.edu/WebPath/PLACHTML/PLAC042.html http://library.med.utah.edu/WebPath/PLACHTML/PLAC042.html]. Accessed on: 12 January 2011.</ref> | |||
*Should be separated from ''squamous metaplasia of amnion''. | |||
===Gross=== | |||
Features:<ref name=pmid18081444>{{Cite journal | last1 = Adeniran | first1 = AJ. | last2 = Stanek | first2 = J. | title = Amnion nodosum revisited: clinicopathologic and placental correlations. | journal = Arch Pathol Lab Med | volume = 131 | issue = 12 | pages = 1829-33 | month = Dec | year = 2007 | doi = 10.1043/1543-2165(2007)131[1829:ANRCAP]2.0.CO;2 | PMID = 18081444 }}</ref> | |||
*Yellow nodules ~ 1-5 mm. | |||
**Some think they are white.<ref>CS. 7 February 2011.</ref> | |||
DDx: | |||
*[[Squamous metaplasia of the amnion]] - large irregular patches, usu. white. | |||
Images: | |||
*[http://www.webpathology.com/image.asp?n=2&Case=659 Amnion nodosum (webpathology.com)]. | |||
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-131-12-1829-f01&doi=10.1043%2F1543-2165%282007%29131%5B1829%3AANRCAP%5D2.0.CO%3B2 Amnion nodosum & squamous metaplasia of the amnion (archivesofpathology.org)].<ref name=pmid18081444/> | |||
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===Microscopic=== | |||
Features:<ref name=pmid18081444/> | |||
*Stratified squamous epithelium - non-keratinizing ''or'' minimal keratin. | |||
*Amorphous acidophilic (pink) debris. | |||
Note: | |||
*Normal amnion = simple epithelium. | |||
Images: | |||
*[http://www.webpathology.com/image.asp?case=659&n=3 Amnion nodosum (webpathology.com)]. | |||
*[http://www.archivesofpathology.org/action/showFullPopup?id=i1543-2165-131-12-1829-f01&doi=10.1043%2F1543-2165%282007%29131%5B1829%3AANRCAP%5D2.0.CO%3B2 Amnion nodosum & squamous metaplasia of the amnion (archivesofpathology.org)].<ref name=pmid18081444/> | |||
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==See also== | |||
*[[Squamous metaplasia]]. | |||
*[[Placenta]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Placenta]] | |||
[[Category:Diagnosis]] | |||