Difference between revisions of "Breast pathology"

Breast pathology (view source)

994 bytes removed , 18:30, 10 March 2016

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 ==Apocrine metaplasia==
-===General===
+{{Main|Apocrine metaplasia of the breast}}
-*Benign/not significant.  Can be considered to be pretty wallpaper in the house of breast pathology.
-====Etiology====
-*Increased number of mitochondria.
-**In other body sites this has different names, e.g. ''[[Hurthle cell change]]'' (thyroid), ''[[oncocytoma|oncocytic]] change'' (kidney - [[oncocytoma]], thyroid).
-===Microscopic===
-Features:
-*Eosinophilic cytoplasm - '''key feature'''.
-*Voluminous pink cytoplasm.
-*Apocrine snouts may be present.
-**Small protrusiona at the apical aspect of the cell (composed of cytoplasm and plasma membrane).
-*Central round nucleus
-**Prominent nuclear membrane.
-**Prominent, often single nucleolus.
-Note:
-*Apocrine changes, i.e. cytoplasmic eosinophilia, can appear in malignant tumours; eosinophilia doesn't make something benign.
-====Images====
-<gallery>
-Image:Fibrocystic_change_-_very_high_mag.jpg | FCC with apocrine metaplasia (right bottom of image) - high mag. (WC/Nephron).
-Image:Breast ApocrineChange HP CTR.jpg|Breast - Apocrine Change - high power (SKB)
-</gallery>
 ==Duct ectasia==