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Difference between revisions of "Parathyroid hyperplasia"
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Parathyroid hyperplasia (view source)
Revision as of 01:50, 26 February 2016
, 01:50, 26 February 2016→Microscopic
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Features:<ref name=Ref_PBoD8_1128>{{Ref PBoD8|1128}}</ref> | Features:<ref name=Ref_PBoD8_1128>{{Ref PBoD8|1128}}</ref> | ||
*Classically have abundant adipose tissue. | *Classically have abundant adipose tissue. | ||
*+/-Water-clear cells | *+/-"Water-clear" cells:<ref name=pmid7487410/> | ||
**Abundant foamy or granular cytoplasm. | |||
**Mild [[nuclear pleomorphism]]. | |||
Note: | Note: | ||
*Generally, it is impossible to discern between [[parathyroid adenoma]]s and [[parathyroid hyperplasia]]s by histology alone.<ref name=Ref_BITFS191>{{Ref BITFS|191}}</ref> | *Generally, it is impossible to discern between [[parathyroid adenoma]]s and [[parathyroid hyperplasia]]s by histology alone.<ref name=Ref_BITFS191>{{Ref BITFS|191}}</ref> | ||
**One requires information of the size of the other glands to make the diagnosis. | **One requires information of the size of the other glands to make the diagnosis. | ||
*Water-clear cells may be seen in an adenoma.<ref name=pmid7487410>{{Cite journal | last1 = Grenko | first1 = RT. | last2 = Anderson | first2 = KM. | last3 = Kauffman | first3 = G. | last4 = Abt | first4 = AB. | title = Water-clear cell adenoma of the parathyroid. A case report with immunohistochemistry and electron microscopy. | journal = Arch Pathol Lab Med | volume = 119 | issue = 11 | pages = 1072-4 | month = Nov | year = 1995 | doi = | PMID = 7487410 }}</ref> | |||
DDx: | DDx: | ||