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*The term "acute" is infrequently used in liver pathology. | *The term "acute" is infrequently used in liver pathology. | ||
*In the liver: neutrophils ''is not'' acute -- unlike most elsewhere in the body.<ref>OA. September 2009.</ref> | *In the liver: neutrophils ''is not'' acute -- unlike most elsewhere in the body.<ref>OA. September 2009.</ref> | ||
===A microscopic checklist=== | |||
<pre> | |||
Size of biopsy: Adequate | |||
Fragmentation: Absent | |||
Fibrosis: Stage 2-3/4, mostly stage 2 | |||
Fibrous septa: Present | |||
Septa with curved contours: Present – focally only | |||
Large droplet steatosis (% of hepatocytes): Present, moderate 60% | |||
Ballooning of hepatocytes: Present, rare | |||
Mallory-Denk bodies: Present, rare | |||
Portal inflammation: Present | |||
Interface activity: Minimal (0-1/4) | |||
Lobular necroinflammation: Minimal | |||
Ducts: Present in normal numbers | |||
Duct injury: Absent | |||
Ductular reaction: Absent | |||
Cholestasis: Absent | |||
Terminal hepatic venules: Present | |||
Iron stain: Absent | |||
Ground glass cells with routine stains: Absent | |||
PASD for alpha-1 antitrypsin droplets: Negative | |||
</pre> | |||
=Liver injury terms/histologic findings= | =Liver injury terms/histologic findings= |
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