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Neuromuscular pathology (view source)
Revision as of 14:42, 8 December 2015
, 14:42, 8 December 2015→Fibre types: Morphology, ATPase
Jensflorian (talk | contribs) (→Work-up: biopsy) |
Jensflorian (talk | contribs) (→Fibre types: Morphology, ATPase) |
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**Nerve (surrounded by ''epineurium'') -> Fascicle (surrounded by ''perineurium'') -> Nerve fibre (surrounded by ''endoneurium''). | **Nerve (surrounded by ''epineurium'') -> Fascicle (surrounded by ''perineurium'') -> Nerve fibre (surrounded by ''endoneurium''). | ||
===Fibre types=== | ===Fibre=== | ||
[[File:1022 Muscle Fibers (small).jpg|500px|right]] | |||
====Fibre morphology==== | |||
*Small or large? | |||
**Related to age? Birth 15µm, 6yrs: 25-30µm, 12yrs: 45µm, adult: 50-60µm. | |||
*Round or angular? | |||
*Architecture: Normal, inclusions, nuclear internalization? | |||
*Pathology distribution: Absent, focal, uniform? | |||
**Pathologic material: Amyloid, Glycogen, Lipid? | |||
====Fibre types==== | |||
{{familytree/start}} | {{familytree/start}} | ||
{{familytree | | | |A11| | | | |A11 =Types }} | {{familytree | | | |A11| | | | |A11 =Types }} | ||
| Line 72: | Line 82: | ||
{{familytree/end}} | {{familytree/end}} | ||
Type 1 - [[AKA]] slow twitch: | Type 1 - [[AKA]] slow twitch: | ||
*Predominantly oxidative metabolism, i.e. have lots of mitochondria. | *Predominantly oxidative metabolism, i.e. have lots of mitochondria. | ||
| Line 124: | Line 133: | ||
| higher | | higher | ||
| lower | | lower | ||
|- | |||
| ATPase pH 9.4 stain | |||
| light brown | |||
| dark brown | |||
|} | |} | ||
</center> | </center> | ||
*Check for fibre type grouping or fibre type predominance. | |||
===Normal findings=== | ===Normal findings=== | ||