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Difference between revisions of "Plasma cell neoplasms"
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==IHC== | ==IHC== | ||
*CD138 +ve. | |||
*[[CD56]] +ve.<ref>URL: [http://www.ncbi.nlm.nih.gov/omim/116930 http://www.ncbi.nlm.nih.gov/omim/116930]. Accessed on: 31 August 2010.</ref> | |||
**Also +ve in NK/T cell lymphomas. | |||
*Kappa -- usu. slightly stronger than lambda. | *Kappa -- usu. slightly stronger than lambda. | ||
*Lambda. | *Lambda. | ||
*CD57. | *CD57. | ||
**Also +ve in [[T-cell large granular lymphocytic leukemia]].<ref>URL: [http://www.nature.com/bmt/journal/v33/n1/full/1704298a.html http://www.nature.com/bmt/journal/v33/n1/full/1704298a.html]. Accessed on: 31 August 2010.</ref> | **Also +ve in [[T-cell large granular lymphocytic leukemia]].<ref>URL: [http://www.nature.com/bmt/journal/v33/n1/full/1704298a.html http://www.nature.com/bmt/journal/v33/n1/full/1704298a.html]. Accessed on: 31 August 2010.</ref> | ||
* | *CD38 +ve.<ref>{{Cite journal | last1 = Tamamori | first1 = T. | last2 = Nakayama | first2 = F. | last3 = Sugimoto | first3 = H. | last4 = Fenxiang | first4 = J. | last5 = Iwatsuki | first5 = K. | last6 = Takigawa | first6 = M. | title = Extramedullary plasmacytoma: cytological and genotypic studies. | journal = Br J Dermatol | volume = 129 | issue = 4 | pages = 468-72 | month = Oct | year = 1993 | doi = | PMID = 8217765 }}</ref> | ||
* | |||
Others:<ref>URL: [http://e-immunohistochemistry.info/web/Plasmacytoma_plasma_cell_myeloma.htm http://e-immunohistochemistry.info/web/Plasmacytoma_plasma_cell_myeloma.htm]. Accessed on: 9 November 2015.</ref> | |||
*CD79a +ve. | |||
*CD45 -ve/+ve. | |||
*CD10 -ve. | |||
*CD5 -ve. | |||
*Cyclin D1 -ve/+ve. | |||
A panel:<!-- need a good panel - maybe here http://clincancerres.aacrjournals.org/content/15/2/714.full or here http://e-immunohistochemistry.info/web/Plasmacytoma_plasma_cell_myeloma.htm --> | |||
*CD3, CD20, CD56, CD117, CD138, IG-kappa (plasma), IG-lambda (plasma). | |||
==Molecular== | ==Molecular== | ||