Difference between revisions of "Breast pathology"

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Breast pathology (view source)

Revision as of 16:22, 14 October 2015

1,322 bytes removed ,  16:22, 14 October 2015
→‎Florid epithelial hyperplasia: split out
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*AKA ''florid epithelial hyperplasia of the usual type'', abbreviated ''FEHUT''.
*AKA ''florid epithelial hyperplasia of the usual type'', abbreviated ''FEHUT''.
*AKA ''epithelial hyperplasia'' - term should be avoid as it could lead to confusion with ''[[mild epithelial hyperplasia]]''.
*AKA ''epithelial hyperplasia'' - term should be avoid as it could lead to confusion with ''[[mild epithelial hyperplasia]]''.
 
{{Main|Florid epithelial hyperplasia}}
===General===
*Mild increased risk of malignancy ~ 1.5-2x.<ref>{{Ref PCPBoD8|542}}</ref>
*Has to be separated from ''[[mild epithelial hyperplasia]]''.
 
Note:
*''Moderate epithelial hyperplasia'' redirects to this section.
**It is generally not separated from FEH, as the prognosis is thought to be the same.
 
===Microscopic===
Features:<ref>{{Ref BP|159-160}}</ref>
*Breast glands with ''more than'' four cell layers above the basement membrane - '''key feature'''.
*Irregular cell spacing; streaming.
*Slit-like lumina, esp. at the periphery of the duct.
*No [[DCIS]]-like architecture (not cribriform, not papillary, not micropapillary, not solid).
*No nuclear atypia - usually no [[nucleoli]].
 
Memory device ''CLEAN'':
*'''C'''ell spacing is irregular, '''L'''umina are slit-like, '''E'''xtent is less than 2 mm or 2 ducts, '''A'''rchitecture ''not'' DCIS-like, '''N'''uclear atypia ''not'' present.
 
DDx:
*[[Mild epithelial hyperplasia]].
*[[Atypical ductal hyperplasia]].
*Cribriform [[ductal carcinoma in situ]]
 
===Sign out===
<pre>
A. Right Breast (570 grams), Reduction Mammoplasty:
- Benign breast tissue with proliferative fibrocystic changes.
- Benign skin.
 
B. Left Breast (580 grams), Reduction Mammoplasty:
- Breast tissue and skin within normal limits.
</pre>
 
Note:
*"Proliferative fibrocystic changes" = [[UDH]] + [[fibrocystic changes]].


==Sclerosing adenosis==
==Sclerosing adenosis==
Michael
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