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Difference between revisions of "Parathyroid adenoma"
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Parathyroid adenoma (view source)
Revision as of 03:32, 11 September 2015
, 03:32, 11 September 2015→Microscopic
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==Microscopic== | ==Microscopic== | ||
Features | Features: | ||
*Proliferation of parathyroid cells (chief cells, oxyphils or both) lacking adipose tissue. | *Proliferation of parathyroid cells (chief cells, oxyphils or both) usually intermixed lacking adipose tissue. | ||
* | *+/-Rim of normal parathyroid gland around the lesion<ref name=Ref_BITFS191>{{Ref BITFS|191}}</ref> with adipose tissue. | ||
Note: | Note: | ||
*Generally, it is impossible to discern between [[parathyroid adenoma]]s and [[parathyroid hyperplasia]]s by histology alone.<ref name=Ref_BITFS191>{{Ref BITFS|191}}</ref> | *Generally, it is impossible to discern between [[parathyroid adenoma]]s and [[parathyroid hyperplasia]]s by histology alone.<ref name=Ref_BITFS191>{{Ref BITFS|191}}</ref> | ||
**One requires information of the size of the other glands to make the diagnosis. | **One requires information of the size of the other glands to make the [[diagnosis]]. | ||
DDx: | DDx: | ||
*[[Parathyroid hyperplasia]] - differentiated by clinical history. | *[[Parathyroid hyperplasia]] - differentiated by clinical history. | ||
*[[Parathyroid carcinoma]] - destructive invasion of surrounding tissue or far away mets, increased proliferative activity. | *[[Parathyroid carcinoma]] - destructive invasion of surrounding tissue or far away mets, increased proliferative activity. | ||
*[[Lymph node]]. | |||
*[[Hürthle cell adenoma]] - for oxyphil type (see below). | |||
*[[Thyroid gland]]. | |||
===Chief cell parathyroid adenoma=== | ===Chief cell parathyroid adenoma=== | ||