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Difference between revisions of "Pediatric pathology"
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{{Main|Wilms tumour}} | {{Main|Wilms tumour}} | ||
Most common abdominal solid organ malignancy in children. | Most common abdominal solid organ malignancy in children. | ||
=Dermatopathology= | |||
{{Main|Dermatopathology}} | |||
==Juvenile xanthogranuloma== | |||
*Abbreviated as ''JXG''. | |||
*[[AKA]] nevoxanthoendothelioma. | |||
===General=== | |||
*Benign skin thingy in children and infants. | |||
===Microscopic=== | |||
Features: | |||
*Dermal histiocytes: | |||
**Abundant cytoplasm - may not be xanthomatous. | |||
*+/-Touton giant cell - '''key feature'''. | |||
Images: | |||
*[http://www.healthcare.uiowa.edu/dermatology/DPT/Hist%5CJXG003.jpg JXG (uiowa.edu)].<ref>URL: [http://www.healthcare.uiowa.edu/dermatology/DPT/Path-Index.htm http://www.healthcare.uiowa.edu/dermatology/DPT/Path-Index.htm]. Accessed on: 3 February 2011.</ref> | |||
Notes: | |||
*Must prove they are non-Langerhans cell histiocytes. | |||
===IHC=== | |||
*Langerhans cell markers: CD1a, CD207 -- both should be negative -- '''key feature'''. | |||
*Histiocyte markers: CD68, CD163 -- both should be positive. | |||
=References= | =References= | ||