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Difference between revisions of "Xanthogranulomatous cystitis"
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==General== | ==General== | ||
*May mimic [[malignancy]].<ref name=pmid25550882>{{Cite journal | last1 = Wang | first1 = Y. | last2 = Han | first2 = XC. | last3 = Zheng | first3 = LQ. | last4 = Miao | first4 = WL. | title = Xanthogranulomatous cystitis imitating bladder neoplasm: a case report and review of literature. | journal = Int J Clin Exp Pathol | volume = 7 | issue = 11 | pages = 8255-8 | month = | year = 2014 | doi = | PMID = 25550882 }}</ref> | *May mimic [[malignancy]].<ref name=pmid25550882>{{Cite journal | last1 = Wang | first1 = Y. | last2 = Han | first2 = XC. | last3 = Zheng | first3 = LQ. | last4 = Miao | first4 = WL. | title = Xanthogranulomatous cystitis imitating bladder neoplasm: a case report and review of literature. | journal = Int J Clin Exp Pathol | volume = 7 | issue = 11 | pages = 8255-8 | month = | year = 2014 | doi = | PMID = 25550882 }}</ref><ref name=pmid25371622>{{Cite journal | last1 = Ali | first1 = AM. | last2 = Nelvigi | first2 = GG. | last3 = Keshavaiah | first3 = VG. | last4 = Ratkal | first4 = CS. | title = Extensive xanthogranulomatous cystitis mimicking bladder cancer. | journal = Urol Ann | volume = 6 | issue = 4 | pages = 373-5 | month = Oct | year = 2014 | doi = 10.4103/0974-7796.141018 | PMID = 25371622 }}</ref> | ||
Clinical features - generally nonspecific:<ref>{{Cite journal | last1 = Grivas | first1 = N. | title = Challenges in the diagnosis of xanthogranulomatous cystitis. | journal = Urol Ann | volume = 6 | issue = 4 | pages = 375-6 | month = Oct | year = 2014 | doi = 10.4103/0974-7796.141019 | PMID = 25371623 }}</ref> | |||
*Dysuria (pain on urination). | |||
*+/-Hematuria. | |||
*Often history of [[renal stones]] or recurrent [[UTI]]s. | |||
==Gross== | |||
*Typically dome of bladder (18 of 27 cases).<ref name=pmid25371622>{{Cite journal | last1 = Ali | first1 = AM. | last2 = Nelvigi | first2 = GG. | last3 = Keshavaiah | first3 = VG. | last4 = Ratkal | first4 = CS. | title = Extensive xanthogranulomatous cystitis mimicking bladder cancer. | journal = Urol Ann | volume = 6 | issue = 4 | pages = 373-5 | month = Oct | year = 2014 | doi = 10.4103/0974-7796.141018 | PMID = 25371622 }}</ref> | |||
==Microscopic== | |||
Features: | |||
*Foamy macrophages. | |||
*Chronic inflammatory cells - typically lymphocytes and plasma cells. | |||
*+/-Cholesterol clefts. | |||
DDx: | |||
*[[Urinary bladder xanthoma]]. | |||
*[[Malakoplakia]]. | |||
*[[Signet ring cell carcinoma]]. | |||
==IHC== | ==IHC== | ||
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==See also== | ==See also== | ||
*[[Xanthogranulomatous pyelonephritis]]. | *[[Xanthogranulomatous pyelonephritis]]. | ||
*[[Granulomatous inflammation]]. | |||
==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Urinary bladder]] | [[Category:Urinary bladder]] | ||