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Difference between revisions of "Pediatric pathology"
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→Gastrointestinal pathology: +CF
(→General: wikify) |
(→Gastrointestinal pathology: +CF) |
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=Gastrointestinal pathology= | =Gastrointestinal pathology= | ||
==Cystic fibrosis== | |||
*Abbreviated ''CF''. | |||
===General=== | |||
*Genetic. | |||
*May lead to meconium ileus. | |||
===Microscopic (large bowel)=== | |||
Features:<ref name=pmid710839>{{cite journal |author=Neutra MR, Trier JS |title=Rectal mucosa in cystic fibrosis. Morphological features before and after short term organ culture |journal=Gastroenterology |volume=75 |issue=4 |pages=701–10 |year=1978 |month=October |pmid=710839 |doi= |url=}}</ref> | |||
*Crypt enlargement. | |||
Notes: | |||
*''Not'' intracellular and extracellular accumulation of mucus. (?) | |||
==Aganglionosis== | ==Aganglionosis== | ||
*[[AKA]] Hirschsprung disease. | *[[AKA]] Hirschsprung disease. | ||
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Pathology: | Pathology: | ||
*Parasympathetic ganglion cells in intramural and submucosal plexuses - not present.<ref name=pathcon_hirschsprung>URL: [[http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970813-0] [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970813-0]]. Accessed on: 11 January 2011.</ref> | *Parasympathetic ganglion cells in intramural and submucosal plexuses - not present.<ref name=pathcon_hirschsprung>URL: [[http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970813-0] [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970813-0]]. Accessed on: 11 January 2011.</ref> | ||
Notes: | |||
*Most common reason for litigation in paediatric pathology.<ref>GT. 19 January 2011.</ref> | |||
===Microscopic=== | ===Microscopic=== | ||