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Difference between revisions of "Thyroid gland"
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→Malignant neoplasm: +HTN
(+lymphoma) |
(→Malignant neoplasm: +HTN) |
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| Line 475: | Line 475: | ||
*Plasma cells. | *Plasma cells. | ||
*"Overgrowth" - thyroid parenchyma displaced by lymphocytes. | *"Overgrowth" - thyroid parenchyma displaced by lymphocytes. | ||
=Weird stuff= | |||
==Hyalinizing trabecular tumour== | |||
===General=== | |||
*[[AKA]] ''hyalinizing trabecular adenoma''. | |||
*Considered by some (e.g. SL Asa) to be a variant of papillary thyroid carcinoma.<ref name=pmid11117782>{{cite journal |author=Cheung CC, Boerner SL, MacMillan CM, Ramyar L, Asa SL |title=Hyalinizing trabecular tumor of the thyroid: a variant of papillary carcinoma proved by molecular genetics |journal=Am. J. Surg. Pathol. |volume=24 |issue=12 |pages=1622–6 |year=2000 |month=December |pmid=11117782 |doi= |url=}}</ref> | |||
*Behaviour similar to papillary thyroid carcinoma - indolent. | |||
===Microscopic=== | |||
Features:<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675(06)71558-3 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675(06)71558-3]. Accessed on: 17 January 2011.</ref> | |||
*Trabecular arrangement of cells. | |||
**May have "curved" trabeculae. | |||
*Extracellular space has hyaline material. | |||
*Cytoplasm mimics hyaline material in the extracellular space. | |||
Image: | |||
*[http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675(06)71558-3&figureId=fig2 Hyalinizing trabecular tumour (pathconsultddx.com)]. | |||
DDx: | |||
*Papillary thyroid carcinoma (if one believes this is a separate entity). | |||
*Medullary thyroid carcinoma. | |||
===IHC=== | |||
*Thyroglobulin +ve. | |||
*NSE +ve. | |||
=See also= | =See also= | ||