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Adenoid cystic/basal cell carcinoma of the prostate (view source)
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'''Adenoid cystic/basal cell carcinoma of the prostate''', abbreviated '''ACBCC''', is a rare from of [[prostate cancer]] that resembles [[adenoid cystic carcinoma]] and [[basal cell carcinoma]]. | |||
==General== | |||
*Rare. | |||
*Typically indolent - may be aggressive.<ref name=pmid14657711>{{Cite journal | last1 = Iczkowski | first1 = KA. | last2 = Ferguson | first2 = KL. | last3 = Grier | first3 = DD. | last4 = Hossain | first4 = D. | last5 = Banerjee | first5 = SS. | last6 = McNeal | first6 = JE. | last7 = Bostwick | first7 = DG. | title = Adenoid cystic/basal cell carcinoma of the prostate: clinicopathologic findings in 19 cases. | journal = Am J Surg Pathol | volume = 27 | issue = 12 | pages = 1523-9 | month = Dec | year = 2003 | doi = | PMID = 14657711 }}</ref> | |||
==Microscopic== | |||
Features: | |||
*[[Adenoid cystic carcinoma]]-like and [[basal cell adenoma]]-like: | |||
**Nests of cells that have round spaces filled by whispy blue mucin. | |||
**Dense collagenous stroma. | |||
===Images=== | |||
<gallery> | |||
Image: Adenoid cystic basal cell carcinoma of the prostate -- intermed mag.jpg | ADBCC - intermed. mag. | |||
Image: Adenoid cystic basal cell carcinoma of the prostate - alt -- intermed mag.jpg | ADBCC - intermed. mag. | |||
Image: Adenoid cystic basal cell carcinoma of the prostate -- high mag.jpg | ADBCC - high mag. | |||
Image: Adenoid cystic basal cell carcinoma of the prostate -- very high mag.jpg | ADBCC - very high mag. | |||
</gallery> | |||
<!-- | |||
Images: | |||
*[http://www.webpathology.com/image.asp?case=23&n=15 Adenoid basal cell tumour (webpathology.com)]. | |||
*[http://www.webpathology.com/image.asp?case=23&n=16 Adenoid basal cell tumour (webpathology.com)]. | |||
--> | |||
===IHC=== | |||
*HER2/neu +ve (strong).<ref name=pmid17142577>{{Cite journal | last1 = Iczkowski | first1 = KA. | last2 = Montironi | first2 = R. | title = Adenoid cystic/basal cell carcinoma of the prostate strongly expresses HER-2/neu. | journal = J Clin Pathol | volume = 59 | issue = 12 | pages = 1327-30 | month = Dec | year = 2006 | doi = 10.1136/jcp.2005.035147 | PMID = 17142577 }}</ref> | |||
==See also== | |||
*[[Prostate cancer]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Prostate carcinoma]] | |||