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Difference between revisions of "TFEB-rearranged renal cell carcinoma"
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TFEB-rearranged renal cell carcinoma (view source)
Revision as of 06:02, 12 January 2015
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = | |||
| Width = | |||
| Caption = | |||
| Synonyms = | |||
| Micro = solid architecture with occasional rosette-like structures; two cell populations (1) large epithelioid cells with clear to eosinophilic cytoplasm, (2) small lymphocyte-like cells | |||
| Subtypes = | |||
| LMDDx = [[renal cell carcinoma, unclassified]], [[angiomyolipoma]] (epithelioid) | |||
| Stains = | |||
| IHC = TFEB +ve (nuclear staining), HMB-45 +ve, TFE3 -ve | |||
| EM = | |||
| Molecular = t(6;11)(p21;q12) | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[kidney]] - see ''[[kidney tumours]]'' | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = children, young adults | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = very rare ~ 2 dozen reported cases | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = agressive (?) | |||
| Other = | |||
| ClinDDx = other [[kidney tumours]] | |||
| Tx = [[nephrectomy]] | |||
}} | |||
'''Renal tumour with t(6;11) translocation''', also '''t(6;11) renal cell carcinoma''', is a rare [[kidney tumour]] seen primarily in children. | '''Renal tumour with t(6;11) translocation''', also '''t(6;11) renal cell carcinoma''', is a rare [[kidney tumour]] seen primarily in children. | ||