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| Caption = Clear cell papillary renal cell carcinoma. [[H&E stain]]. | | Caption = Clear cell papillary renal cell carcinoma. [[H&E stain]]. | ||
| Synonyms = clear cell tubulopapillary renal cell carcinoma | | Synonyms = clear cell tubulopapillary renal cell carcinoma | ||
| Micro = apical nuclei, clear cells, pseudopapillae, cystic and/or tubular architectures | | Micro = low ([[ISUP nucleolar grade|ISUP nucleolar]]) grade apical nuclei, clear cells, pseudopapillae, cystic and/or tubular architectures | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[papillary renal cell carcinoma]], [[clear cell renal cell carcinoma]], [[Xp11.2 translocation carcinoma]] | | LMDDx = [[papillary renal cell carcinoma]], [[clear cell renal cell carcinoma]], [[Xp11.2 translocation carcinoma]] | ||
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*#Papillary RCC. | *#Papillary RCC. | ||
*#*Pseudopapillae - often do not have true papillae. | *#*Pseudopapillae - often do not have true papillae. | ||
*Apical nuclei ‡ - '''key feature'''.<ref name=bing>{{Cite journal | last1 = Bing | first1 = Z. | last2 = Tomaszewski | first2 = JE. | title = Case Report: Clear Cell Papillary Renal Cell Carcinoma in the Bilateral Native Kidneys after 2 Years of Renal Transplantation: Report of a Case and Review of the Literature. | journal = Case Reports in Transplantation | volume = 2011 | issue = | pages = | month = | year = 2011 | doi = 10.1155/2011/387645 | PMID = | url = http://www.hindawi.com/crim/transplantation/2011/387645/cta/ }}</ref> | *Apical nuclei - should be predominant ‡ - '''key feature'''.<ref name=bing>{{Cite journal | last1 = Bing | first1 = Z. | last2 = Tomaszewski | first2 = JE. | title = Case Report: Clear Cell Papillary Renal Cell Carcinoma in the Bilateral Native Kidneys after 2 Years of Renal Transplantation: Report of a Case and Review of the Literature. | journal = Case Reports in Transplantation | volume = 2011 | issue = | pages = | month = | year = 2011 | doi = 10.1155/2011/387645 | PMID = | url = http://www.hindawi.com/crim/transplantation/2011/387645/cta/ }}</ref> | ||
**In most glandular structures the nuclei are usu. basally located, i.e. in the cytoplasm adjacent to the basement membrane. | **In most glandular structures the nuclei are usu. basally located, i.e. in the cytoplasm adjacent to the basement membrane. | ||
*Tubular and/or cystic architecture. | *Tubular and/or cystic architecture. | ||
Notes: ‡ | |||
* | *Apical nuclei may be seen focally in [[clear cell renal cell carcinoma]]. | ||
*Nuclei should be low grade ([[ISUP nucleolar grade]] 1 or 2). | |||
DDx: | DDx: |
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