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| :'''Not''' to be confused with ''[[ganglioglioma]]''. | | :'''Not''' to be confused with ''[[ganglioglioma]]''. |
| *[[AKA]] ganglioma.<ref>URL: [http://medical-dictionary.thefreedictionary.com/ganglioma http://medical-dictionary.thefreedictionary.com/ganglioma]. Accessed on: 8 November 2010.</ref> | | *[[AKA]] ganglioma.<ref>URL: [http://medical-dictionary.thefreedictionary.com/ganglioma http://medical-dictionary.thefreedictionary.com/ganglioma]. Accessed on: 8 November 2010.</ref> |
| ===General===
| | {{Main|Ganglioneuroma}} |
| *May be retroperitoneal.
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| *Occasionally found in the GI tract - may form [[Gastrointestinal_tract_polyps#Ganglioneuroma|colonic polyp]].
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| *Multiple ganglioneuromas may be due to [[multiple endocrine neoplasia IIb]].
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| Classification:
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| *In a grouping known as ''neuroblastic tumours'' which includes:<ref name=pmid10421272>{{cite journal |author=Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B |title=Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee |journal=Cancer |volume=86 |issue=2 |pages=349–63 |year=1999 |month=July |pmid=10421272 |doi= |url=}}</ref>
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| **Ganglioneuroma (benign).
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| **[[Ganglioneuroblastoma]] (intermediate).
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| **[[Neuroblastoma]] (aggressive).
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| ===Gross===
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| *Solid.
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| *White.
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| *Firm.
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| *Well-circumscribed.
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| *May be nodular.
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| Images:
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| *[http://commons.wikimedia.org/wiki/File:Adrenal_ganglioneuroma_02.JPG Adrenal ganglioneuroma (WC)].
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| *[http://www.webpathology.com/image.asp?case=84&n=1 Ganglioneuroma (webpathology.com)].
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| ===Microscopic===
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| Features:
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| *Ganglion cells - '''key feature'''.
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| **Large cells with large nucleus.
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| ***Prominent nucleolus.
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| *Disordered fibrinous-like material.
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| *Eosinophilic granular bodies.<ref>R. Kiehl. 8 November 2010.</ref>
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| Images:
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| *[http://it.wikipedia.org/wiki/File:Ganglioneuroma_(1).jpg Ganglioneuroma (WC)].
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| *[http://www.webpathology.com/image.asp?n=4&Case=84 Ganglioneuroma (webpathology.com)].
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| *[http://www.webpathology.com/image.asp?case=412&n=4 Ganglioneuroma (webpathology.com)].
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| *[http://en.wikipedia.org/wiki/File:Ganglion_high_mag.jpg Normal ganglion - high mag. (WC)] .
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| See: ''[[adrenal ganglioneuroma]]'', ''[[Gastrointestinal tract polyps#Ganglioneuroma|colonic ganglioneuroma]]''.
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| ===IHC===
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| Features:<ref>{{Ref GLP|217}}</ref>
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| *Spindle cells: S-100 +ve.
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| *Ganglion cells: NSE, synaptophysin, NF.
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| ==Ependymoma== | | ==Ependymoma== |