Difference between revisions of "Neuropathology tumours"

Neuropathology tumours (view source)

464 bytes removed , 06:51, 10 December 2014

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 ==Oligoastrocytoma==
-===General===
+{{Main|Oligoastrocytoma}}
-*Mixed tumour.
-===Microscopic===
-Features:
-*Astrocytoma-like and oligodendroglioma-like:
-*#Oligodendroglioma-like cells = round nucleus, peri-nuclear clearing.
-*#Astrocytoma-like cells = non-ovoid/elongated nucleus.
-DDx:
-*Anaplastic astrocytoma.
-*Oligodendroglioma. (???)
-===IHC===
-*Oligodendroglioma-like cells: MAP-2 +ve (cytoplasm).
-*Astrocytoma-like cells: GFAP +ve (cytoplasm, nuclear membrane).
-Others:
-*Ki-67 ~10%. (???)
-*p53 - focally +ve. (???)
-*IDH-1 +ve. (85%)
 ==Meningioma==