Difference between revisions of "Chondrosarcoma"

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*This is where the name comes from.<ref name=pmid14161087>{{cite journal |author=Dowling EA |title=Mesenchymal chondrosarcoma |journal=J Bone Joint Surg Am |volume=46 |issue= |pages=747–54 |year=1964 |month=June |pmid=14161087 |doi= |url=http://www.ejbjs.org/cgi/reprint/46/4/747.pdf}}</ref>
*This is where the name comes from.<ref name=pmid14161087>{{cite journal |author=Dowling EA |title=Mesenchymal chondrosarcoma |journal=J Bone Joint Surg Am |volume=46 |issue= |pages=747–54 |year=1964 |month=June |pmid=14161087 |doi= |url=http://www.ejbjs.org/cgi/reprint/46/4/747.pdf}}</ref>
==Gross==
Pink and fleshy with foci of calcification.
==Microscopic==
*"White clouds in a blue sky".
*Malignant tumor with a characteristic biphasic pattern
**Cellular poorly differentiated small round blue cells
**Islands of well-differentiated hyaline cartilage
***Progressive maturation of cartilage towards the center
***Central calcification or bone formation
==IHC==
*SOX9 (positive in small cells and chondrocytes)
*S100 (positive in chondrocytes)
*Osteocalcin (negative in small cells)
==Molecular==
t(8;8)(q21.1;q13.3) HEY1-NCOA2
==Photos==
<gallery>
*[[File:Bone Chondrosarcoma Mesenchymal MP5 PA.JPG|Islands of cartilage in a background of small blue cells.]]
*[[File:Bone Chondrosarcoma Mesenchymal MP PA.JPG|Islands of cartilage in a background of small blue cells.]]
*[[File:Bone Chondrosarcoma Mesenchymal LP2 PA.JPG|Islands of cartilage in a background of small blue cells.]]
*[[File:Bone Chondrosarcoma Mesenchymal HP5 PA.JPG|Islands of cartilage in a background of small blue cells.]]
*[[File:Bone Chondrosarcoma Mesenchymal MP2 PA.JPG|Islands of cartilage in a background of small blue cells.]]
*[[File:Bone Chondrosarcoma Mesenchymal MP7.JPG|Islands of cartilage in a background of small blue cells.]]
*[[File:Bone Chondrosarcoma Mesenchymal HP3 PA.JPG|Small blue cells predominate]]
</gallery>
==See also==
Image:
*[http://moon.ouhsc.edu/kfung/jty1/opaq/PathQuiz/S0A001-PQ01-M.htm Mesenchymal chondrosarcoma (ouhsc.edu)].
==References==
{{Reflist|1}}


====Myxoid chondrosarcoma====
====Myxoid chondrosarcoma====
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