17
edits
Difference between revisions of "Oligodendroglioma"
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→IHC
(→IHC) |
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Features: | Features: | ||
*MAP-2 +ve.<reF name=pmid12025943>{{cite journal |author=Suzuki SO, Kitai R, Llena J, Lee SC, Goldman JE, Shafit-Zagardo B |title=MAP-2e, a novel MAP-2 isoform, is expressed in gliomas and delineates tumor architecture and patterns of infiltration |journal=J. Neuropathol. Exp. Neurol. |volume=61 |issue=5 |pages=403–12 |year=2002 |month=May |pmid=12025943 |doi= |url=}}</ref> | *MAP-2 +ve.<reF name=pmid12025943>{{cite journal |author=Suzuki SO, Kitai R, Llena J, Lee SC, Goldman JE, Shafit-Zagardo B |title=MAP-2e, a novel MAP-2 isoform, is expressed in gliomas and delineates tumor architecture and patterns of infiltration |journal=J. Neuropathol. Exp. Neurol. |volume=61 |issue=5 |pages=403–12 |year=2002 |month=May |pmid=12025943 |doi= |url=}}</ref> | ||
*GFAP | *GFAP +ve (variable). | ||
**Some subtypes +ve - should not be used to distinguish.<ref name=Ref_PSNP>{{Ref PSNP|98}}</ref> | **Some subtypes +ve - should not be used to distinguish.<ref name=Ref_PSNP>{{Ref PSNP|98}}</ref> | ||
*EMA +ve. | *EMA +ve. | ||
*IDH-1 | *IDH-1 +ve. (80%). | ||
*p53 -ve. | *p53 -ve. | ||
**Useful for differentiating ''astrocytoma'' vs. ''oligodendroglioma''. | **Useful for differentiating ''astrocytoma'' vs. ''oligodendroglioma''. | ||