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Difference between revisions of "Pediatric pathology"
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→Hypoxic-ischemic encephalopathy
m (moved Paediatric pathology to Pediatric pathology: to American spelling) |
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==Hypoxic-ischemic encephalopathy== | ==Hypoxic-ischemic encephalopathy== | ||
{{Main|Neuropathology}} | {{Main|Neuropathology}} | ||
*Abbreviated ''HIE''. | |||
*Autopsy adds some information. | *Autopsy adds some information. | ||
*Two-tone liver - suggests prior injury.<ref name=pmid15957995>{{cite journal |author=Elder DE, Zuccollo JM, Stanley TV |title=Neonatal death after hypoxic ischaemic encephalopathy: does a postmortem add to the final diagnoses? |journal=BJOG |volume=112 |issue=7 |pages=935–40 |year=2005 |month=July |pmid=15957995 |doi=10.1111/j.1471-0528.2005.00608.x |url=}}</ref> | *Two-tone liver - suggests prior injury.<ref name=pmid15957995>{{cite journal |author=Elder DE, Zuccollo JM, Stanley TV |title=Neonatal death after hypoxic ischaemic encephalopathy: does a postmortem add to the final diagnoses? |journal=BJOG |volume=112 |issue=7 |pages=935–40 |year=2005 |month=July |pmid=15957995 |doi=10.1111/j.1471-0528.2005.00608.x |url=}}</ref> | ||
*HIE in perinatal period may be unique to the specific time of the injury, i.e. the type of hypoxic insults vary by developmental stage.<ref name=pmid11876572>{{cite journal |author=Grafe MR, Kinney HC |title=Neuropathology associated with stillbirth |journal=Semin. Perinatol. |volume=26 |issue=1 |pages=83–8 |year=2002 |month=February |pmid=11876572 |doi= |url=}}</ref> | |||
**Some hypoxic injuries that are prenatal do not occur after birth. | |||
**Hypoxic-ischemic insults are predominantly in the white matter. | |||
==References== | ==References== | ||