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Difference between revisions of "Esophagus"
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→Adenocarcinoma of the esophagus: +images, +grading
(→Barrett's esophagus: +image, chg format) |
(→Adenocarcinoma of the esophagus: +images, +grading) |
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| Line 295: | Line 295: | ||
*May be difficult to distinguish from adenocarcinoma of the stomach. | *May be difficult to distinguish from adenocarcinoma of the stomach. | ||
===Tx=== | ====Tx==== | ||
*Adenocarcinoma in situ (AIS) - may be treated with endoscopic mucosal resection & follow-up.<ref name=pmid19306943/> | *Adenocarcinoma in situ (AIS) - may be treated with endoscopic mucosal resection & follow-up.<ref name=pmid19306943/> | ||
*Surgery - esophagectomy. | *Surgery - esophagectomy. | ||
===Microscopic=== | |||
Features: | |||
*Adenocarcinoma: | |||
**Cell clusters that form glands. | |||
**Nuclear atypia of malignancy: | |||
***Size variation. | |||
***Shape variation. | |||
***Staining variation. | |||
**Mitoses common. | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Esophageal_adenocarcinoma_-_very_low_mag.jpg Esophageal adenocarcinoma - very low mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Esophageal_adenocarcinoma_-_intermed_mag.jpg Esophageal adenocarcinoma - intermed. mag. (WC)]. | |||
====Grading==== | |||
Graded like other adenocarcinoma:<ref name=Ref_WMSP168>{{Ref WMSP|168}}</ref> | |||
*Well-differentiated >95 % of tumour in glandular arrangement. | |||
*Moderately-differentiated 95-50% of tumour in glandular arrangement. | |||
*Poorly-differentiated <50% of tumour in glandular arrangment. | |||
===IHC=== | ===IHC=== | ||