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(→Useful stains: wikify) |
(→Barrett's esophagus: +image, chg format) |
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==Barrett's esophagus== | ==Barrett's esophagus== | ||
=== | ===General=== | ||
*Metaplastic transformation of stratified squamous epithelium to simple columnar epithelium with goblet cells. | *Diagnosis is clinical. | ||
**Pathologic correlate: | |||
***Metaplastic transformation of stratified squamous epithelium to simple columnar epithelium with goblet cells. | |||
*Associated with chronic reflux. | |||
====Significance of Barrett's esophagus==== | |||
*Increased risk of adenocarcinoma of the esophagus. | |||
**Need on-going surveillance, i.e. long term follow-up/repeat esophagogastroduodenoscopy. | |||
===Microscopic=== | ===Microscopic=== | ||
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*Goblets cells -- '''key feature'''. | *Goblets cells -- '''key feature'''. | ||
Images: | |||
* | *[http://commons.wikimedia.org/wiki/File:Barretts_alcian_blue.jpg Barrett's esophagus - alcian blue (WC)]. | ||
==Gastroesophageal reflux disease== | ==Gastroesophageal reflux disease== |
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