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Difference between revisions of "Esophageal adenocarcinoma"
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = | | Image = Esophageal_adenocarcinoma_-_high_mag.jpg | ||
| Width = | | Width = | ||
| Caption = | | Caption = Esophageal adenocarcinoma. [[H&E stain]]. | ||
| Synonyms = | | Synonyms = | ||
| Micro = | | Micro = | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = | | LMDDx = [[high-grade columnar dysplasia of the esophagus]], [[squamous cell carcinoma of the esophagus]],[[gastric adenocarcinoma]] | ||
| Stains = | | Stains = CK7 +ve, CK20 +ve, p63 -ve | ||
| IHC = | | IHC = | ||
| EM = | | EM = | ||
| Line 49: | Line 49: | ||
Features: | Features: | ||
*Adenocarcinoma: | *Adenocarcinoma: | ||
** | **"Invading" cell clusters or glands. | ||
***Cribriforming (more than rare) or desmoplasia or "deep" invasion (into submucosa). | |||
**Nuclear atypia of malignancy: | **Nuclear atypia of malignancy: | ||
***Size variation. | ***Size variation. | ||
***Shape variation. | ***Shape variation. | ||
***Staining variation. | ***Staining variation. | ||
**Mitoses common. | **+/-Mitoses (common). | ||
DDx: | DDx: | ||
*[[Columnar dysplasia of the esophagus|High-grade columnar dysplasia of the esophagus]] | *[[Columnar dysplasia of the esophagus|High-grade columnar dysplasia of the esophagus]] - see table in ''[[esophagus]]'' article | ||
*[[Squamous cell carcinoma of the esophagus]]. | *[[Squamous cell carcinoma of the esophagus]]. | ||
*[[Gastric adenocarcinoma]]. | *[[Gastric adenocarcinoma]]. | ||
| Line 66: | Line 67: | ||
Image:Esophageal_adenocarcinoma_-_low_mag.jpg |Esophageal adenocarcinoma - low mag. (WC) | Image:Esophageal_adenocarcinoma_-_low_mag.jpg |Esophageal adenocarcinoma - low mag. (WC) | ||
Image:Esophageal_adenocarcinoma_-_intermed_mag.jpg |Esophageal adenocarcinoma - intermed. mag. (WC) | Image:Esophageal_adenocarcinoma_-_intermed_mag.jpg |Esophageal adenocarcinoma - intermed. mag. (WC) | ||
Image:Esophageal_adenocarcinoma_-_high_mag.jpg |Esophageal adenocarcinoma - high mag. (WC) | |||
</gallery> | </gallery> | ||
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==See also== | ==See also== | ||
*[[Esophagus]]. | *[[Esophagus]]. | ||
*[[Adenocarcinoma]]. | |||
==References== | ==References== | ||