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Difference between revisions of "B cell small lymphocytic lymphoma/chronic lymphocytic leukemia"
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B cell small lymphocytic lymphoma/chronic lymphocytic leukemia (view source)
Revision as of 12:55, 10 June 2014
, 12:55, 10 June 2014no edit summary
| Line 15: | Line 15: | ||
| Gross = | | Gross = | ||
| Grossing = | | Grossing = | ||
| Site = [[bone marrow]]/[[lymph nodes]] | | Site = blood + [[bone marrow]]/[[lymph nodes]] | ||
| Assdx = | | Assdx = | ||
| Syndromes = | | Syndromes = | ||
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| Symptoms = | | Symptoms = | ||
| Prevalence = common | | Prevalence = common | ||
| Bloodwork = | | Bloodwork = elevated WBC (≥5 × 10<sup>9</sup>/L) | ||
| Rads = | | Rads = | ||
| Endoscopy = | | Endoscopy = | ||
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| Other = | | Other = | ||
| ClinDDx = | | ClinDDx = | ||
| Tx = | | Tx = often followup | ||
}} | }} | ||
'''B cell small lymphocytic lymphoma/chronic lymphocytic leukemia''', often referred to as '''chronic lymphocytic leukemia''' (abbreviated '''CLL''') or '''small lymphocytic lymphoma''' (abbreviated '''SLL'''), is a common low-grade hematologic [[malignancy]]. It typically afflicts older individuals. | '''B cell small lymphocytic lymphoma/chronic lymphocytic leukemia''', often referred to as '''chronic lymphocytic leukemia''' (abbreviated '''CLL''') or '''small lymphocytic lymphoma''' (abbreviated '''SLL'''), is a common low-grade hematologic [[malignancy]]. It typically afflicts older individuals. | ||
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**May transform to an aggressive lymphoma - see below. | **May transform to an aggressive lymphoma - see below. | ||
*Older individuals. | *Older individuals. | ||
*Elevated WBC. | *Elevated WBC ≥5 × 10<sup>9</sup>/L - required for diagnosis (clinically).<ref>{{cite journal |author=Call TG, Norman AD, Hanson CA, ''et al.'' |title=Incidence of chronic lymphocytic leukemia and high-count monoclonal B-cell lymphocytosis using the 2008 guidelines |journal=Cancer |volume= |issue= |pages= |year=2014 |month=April |pmid=24711224 |doi=10.1002/cncr.28690 |url=}}</ref> | ||
===Richter's transformation=== | ===Richter's transformation=== | ||