48,830
edits
Difference between revisions of "Glassy cell carcinoma"
Jump to navigation
Jump to search
no edit summary
(split out) |
|||
| Line 1: | Line 1: | ||
{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Glassy_cell_carcinoma_-_high_mag.jpg | |||
| Width = | |||
| Caption = Glassy cell carcinoma. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = epithelioid cells in sheets or cords with a round/oval nucleus, one or more prominent nucleoli, abundant finely vacuolated eosinophilic to amphophilic cytoplasm, distinct cell borders, inflammation - especially eosinophils | |||
| Subtypes = | |||
| LMDDx = [[Adenosquamous carcinoma|adenosquamous carcinoma of the uterine cervix]], [[squamous carcinoma of the uterine cervix]] | |||
| Stains = [[PAS stain]] +ve (plasma membrane) | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[uterine cervix]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = rapid growth | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = rare | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = poor | |||
| Other = | |||
| ClinDDx = other [[uterine cervix|cervical]] tumours | |||
| Tx = | |||
}} | |||
'''Glassy cell carcinoma''', abbreviated '''GCC''', is a rare [[malignancy]] of the [[uterine cervix]]. | '''Glassy cell carcinoma''', abbreviated '''GCC''', is a rare [[malignancy]] of the [[uterine cervix]]. | ||
| Line 8: | Line 39: | ||
==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid11393075>{{Cite journal | last1 = Reis-Filho | first1 = JS. | last2 = Fillus Neto | first2 = J. | last3 = Schonemann | first3 = E. | last4 = Sanderson | first4 = A. | last5 = Schmitt | first5 = FC. | title = Glassy cell carcinoma of the uterine cervix. Report of a case with cytohistologic and immunohistochemical study. | journal = Acta Cytol | volume = 45 | issue = 3 | pages = 407-10 | month = | year = | doi = | PMID = 11393075 }}</ref> | Features:<ref name=pmid11393075>{{Cite journal | last1 = Reis-Filho | first1 = JS. | last2 = Fillus Neto | first2 = J. | last3 = Schonemann | first3 = E. | last4 = Sanderson | first4 = A. | last5 = Schmitt | first5 = FC. | title = Glassy cell carcinoma of the uterine cervix. Report of a case with cytohistologic and immunohistochemical study. | journal = Acta Cytol | volume = 45 | issue = 3 | pages = 407-10 | month = | year = | doi = | PMID = 11393075 }}</ref> | ||
*Epithelioid cells in sheets or cords | *Epithelioid cells in sheets or cords with: | ||
*Round/oval nucleus. | **Round/oval nucleus. | ||
*One or more prominent nucleoli. | **One or more prominent nucleoli. | ||
*Abundant finely vacuolated eosinophilic to amphophilic cytoplasm. | **Abundant finely vacuolated eosinophilic to amphophilic cytoplasm. | ||
*Distinct cell borders. | **Distinct cell borders. | ||
*Inflammation - esp. eosinophils.<ref>URL: [http://www.webpathology.com/image.asp?n=2&Case=561 http://www.webpathology.com/image.asp?n=2&Case=561]. Accessed on: 4 September 2011.</ref> | *Inflammation - esp. eosinophils.<ref>URL: [http://www.webpathology.com/image.asp?n=2&Case=561 http://www.webpathology.com/image.asp?n=2&Case=561]. Accessed on: 4 September 2011.</ref> | ||