Difference between revisions of "Classic vulvar intraepithelial neoplasia"

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- CLASSIC VULVAR INTRAEPITHELIAL NEOPLASIA (VIN) I (MILD DYSPLASIA).
- CLASSIC VULVAR INTRAEPITHELIAL NEOPLASIA (VIN) I (MILD DYSPLASIA).
- NEGATIVE FOR INVASIVE MALIGNANCY.
- NEGATIVE FOR INVASIVE MALIGNANCY.
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====VIN II====
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LEFT LABIUM MINUS, PUNCH BIOPSY:
- CLASSIC VULVAR INTRAEPITHELIAL NEOPLASIA (cVIN) II (MODERATE DYSPLASIA).
- LICHEN SCLEROSUS.
COMMENT:
Immunostains:
POSITIVE: p16 (strong, diffuse - lower 2/3 of the epithelium).
NEGATIVE: HMB-45, S-100, p53 (weak, patchy, superficial squamous cells).
PROLIFERATION (Ki-67): increased, marks superficial squamous cells (compatible with
                        high-grade lesion).
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