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- CLASSIC VULVAR INTRAEPITHELIAL NEOPLASIA (VIN) I (MILD DYSPLASIA). | - CLASSIC VULVAR INTRAEPITHELIAL NEOPLASIA (VIN) I (MILD DYSPLASIA). | ||
- NEGATIVE FOR INVASIVE MALIGNANCY. | - NEGATIVE FOR INVASIVE MALIGNANCY. | ||
</pre> | |||
====VIN II==== | |||
<pre> | |||
LEFT LABIUM MINUS, PUNCH BIOPSY: | |||
- CLASSIC VULVAR INTRAEPITHELIAL NEOPLASIA (cVIN) II (MODERATE DYSPLASIA). | |||
- LICHEN SCLEROSUS. | |||
COMMENT: | |||
Immunostains: | |||
POSITIVE: p16 (strong, diffuse - lower 2/3 of the epithelium). | |||
NEGATIVE: HMB-45, S-100, p53 (weak, patchy, superficial squamous cells). | |||
PROLIFERATION (Ki-67): increased, marks superficial squamous cells (compatible with | |||
high-grade lesion). | |||
</pre> | </pre> | ||
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