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|
Line 171: |
Line 171: |
| *AKA ''benign prostatic hypertrophy''. | | *AKA ''benign prostatic hypertrophy''. |
| **This is a misnomer. It is ''not'' a hypertrophy. | | **This is a misnomer. It is ''not'' a hypertrophy. |
| | | {{Main|Nodular hyperplasia of the prostate}} |
| ===General===
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| *Very common.
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| *Incidence increases with age.
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| | |
| Clinical - mnemonic ''I WISH 2p'':<ref>{{Ref TN2006| U5}}</ref>
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| *Intermittency.
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| *Weak stream.
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| *Incomplete emptying.
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| *Straining.
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| *Hesitancy.
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| *Post-void dribbling.
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| *Prolonged voiding.
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| | |
| Treatment:
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| *Medications.
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| *Transurethral resection of the prostate (TURP).
| |
| | |
| ===Microscopic===
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| Features:
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| *Stromal and/or glandular hyperplasia.
| |
| | |
| Note:
| |
| *Should '''not''' be diagnosed on core biopsy!
| |
| | |
| DDx:
| |
| *[[Urothelial carcinoma]] - significant nuclear atypia.
| |
| | |
| ====Images====
| |
| <gallery>
| |
| Image:Nodular_hyperplasia_of_the_prostate.jpg | Prostatic nodular hyperplasia. (WC/Nephron)
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| Image:Urethral_urothelial_cell_carcinoma.jpg | UCC. (WC/Nephron)
| |
| </gallery>
| |
| | |
| ===Sign out===
| |
| ====Urothelium present====
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| <pre>
| |
| PROSTATE TISSUE, TRANSURETHRAL RESECTION OF THE PROSTATE (TURP):
| |
| - BENIGN PROSTATIC TISSUE WITH GLANDULAR AND STROMAL PROLIFERATION.
| |
| - UROTHELIAL MUCOSA WITH A MILD LYMPHOCYTIC INFILTRATE.
| |
| - NEGATIVE FOR MALIGNANCY.
| |
| </pre>
| |
| | |
| <pre>
| |
| PROSTATE TISSUE, TRANSURETHRAL RESECTION OF THE PROSTATE (TURP) AND URINARY BLADDER NECK:
| |
| - BENIGN PROSTATIC TISSUE WITH GLANDULAR AND STROMAL PROLIFERATION.
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| - UROTHELIUM WITH THE CHANGES OF CYSTITIS CYSTICA ET GLANDULARIS.
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| - NEGATIVE FOR MALIGNANCY.
| |
| </pre>
| |
| | |
| <pre>
| |
| PROSTATE TISSUE, TRANSURETHRAL RESECTION OF THE PROSTATE (TURP) AND URINARY BLADDER NECK:
| |
| - BENIGN PROSTATIC TISSUE WITH GLANDULAR AND STROMAL PROLIFERATION, AND FOCAL
| |
| ACUTE AND CHRONIC INFLAMMATION.
| |
| - UROTHELIUM WITH THE CHANGES OF CYSTITIS CYSTICA ET GLANDULARIS.
| |
| - NEGATIVE FOR MALIGNANCY.
| |
| </pre>
| |
| | |
| ====No urothelium present====
| |
| <pre>
| |
| PROSTATE GLAND, TRANSURETHRAL RESECTION OF THE PROSTATE (TURP):
| |
| - BENIGN PROSTATIC TISSUE WITH GLANDULAR AND STROMAL PROLIFERATION.
| |
| </pre>
| |
| | |
| ====Post-TURP granuloma present====
| |
| <pre>
| |
| PROSTATE TISSUE, TRANSURETHRAL RESECTION OF THE PROSTATE (TURP):
| |
| - BENIGN PROSTATIC TISSUE WITH GLANDULAR AND STROMAL PROLIFERATION WITH
| |
| PROMINENT BLOOD VESSELS AND SQUAMOUS METAPLASIA.
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| - PALISADING GRANULOMA WITH NECROTIC CORE, SEE COMMENT.
| |
| - UROTHELIAL MUCOSA WITH A MILD INFLAMMATORY INFILTRATE.
| |
| - NEGATIVE FOR MALIGNANCY.
| |
| | |
| COMMENT:
| |
| This is morphologically consistent with a post-TURP granuloma.
| |
| </pre>
| |
|
| |
|
| ==Acute inflammation of the prostate gland== | | ==Acute inflammation of the prostate gland== |