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Difference between revisions of "Juvenile granulosa cell tumour"
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Juvenile granulosa cell tumour (view source)
Revision as of 03:56, 18 February 2014
, 03:56, 18 February 2014no edit summary
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Juvenile_granulosa_cell_tumour_-_very_high_mag.jpg | |||
| Width = | |||
| Caption = Juvenile granulosa cell tumour. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = microcystic spaces, cuboidal-to-polygonal cells in sheets or stands or cords, with moderate-to-marked nuclear atypia, and basophilic cytoplasm | |||
| Subtypes = | |||
| LMDDx = [[Brenner tumour]] | |||
| Stains = | |||
| IHC = inhibin +ve, calretinin +ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = mass lesion, solid | |||
| Grossing = | |||
| Site = [[ovary]] - ''[[ovarian tumours]]'' | |||
| Assdx = [[endometrial hyperplasia]], [[endometrioid endometrial carcinoma]] | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = +/-menorrhagia | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Juvenile granulosa cell tumour''' is an uncommon [[ovarian tumour]] in the ''sex cord stromal tumours'' group. | '''Juvenile granulosa cell tumour''' is an uncommon [[ovarian tumour]] in the ''sex cord stromal tumours'' group. | ||
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**May present as precocious puberty.<ref name=pmid21526089>{{Cite journal | last1 = Hashemipour | first1 = M. | last2 = Moaddab | first2 = MH. | last3 = Nazem | first3 = M. | last4 = Mahzouni | first4 = P. | last5 = Salek | first5 = M. | title = Granulosa cell tumor in a six-year-old girl presented as precocious puberty. | journal = J Res Med Sci | volume = 15 | issue = 4 | pages = 240-2 | month = Jul | year = 2010 | doi = | PMID = 21526089 }}</ref> | **May present as precocious puberty.<ref name=pmid21526089>{{Cite journal | last1 = Hashemipour | first1 = M. | last2 = Moaddab | first2 = MH. | last3 = Nazem | first3 = M. | last4 = Mahzouni | first4 = P. | last5 = Salek | first5 = M. | title = Granulosa cell tumor in a six-year-old girl presented as precocious puberty. | journal = J Res Med Sci | volume = 15 | issue = 4 | pages = 240-2 | month = Jul | year = 2010 | doi = | PMID = 21526089 }}</ref> | ||
*Reported in males.<ref>URL: [http://path.upmc.edu/cases/case631.html http://path.upmc.edu/cases/case631.html]. Accessed on: 26 January 2012.</ref> | *Reported in males.<ref>URL: [http://path.upmc.edu/cases/case631.html http://path.upmc.edu/cases/case631.html]. Accessed on: 26 January 2012.</ref> | ||
*Uncommon.<ref name=pmid23033282>{{Cite journal | last1 = Oztekin | first1 = D. | last2 = Kurt | first2 = S. | last3 = Camuzcuoglu | first3 = H. | last4 = Balsak | first4 = D. | last5 = Dicle | first5 = N. | last6 = Tinar | first6 = S. | title = Granulosa cell tumors of the ovary: review of 43 cases. | journal = J BUON | volume = 17 | issue = 3 | pages = 461-4 | month = | year = | doi = | PMID = 23033282 }}</ref> | |||
==Gross== | ==Gross== | ||
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Notes: | Notes: | ||
*Juvenile variant of GCT has more nuclear pleomorphism. | *Juvenile variant of GCT has more nuclear pleomorphism. | ||
DDx: | |||
*[[Brenner tumour]]. | |||
===Images=== | ===Images=== | ||