Difference between revisions of "Breast pathology"

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Breast pathology (view source)

Revision as of 04:40, 16 February 2014

1,418 bytes removed ,  04:40, 16 February 2014
→‎Lymphocytic mastitis: split out
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==Lymphocytic mastitis==
==Lymphocytic mastitis==
===General===
{{Main|Lymphocytic mastitis}}
*If the individual has [[diabetes mellitus]] (DM) it is called ''diabetic mastopathy''.<ref name=pmid12640102>{{Cite journal  | last1 = Valdez | first1 = R. | last2 = Thorson | first2 = J. | last3 = Finn | first3 = WG. | last4 = Schnitzer | first4 = B. | last5 = Kleer | first5 = CG. | title = Lymphocytic mastitis and diabetic mastopathy: a molecular, immunophenotypic, and clinicopathologic evaluation of 11 cases. | journal = Mod Pathol | volume = 16 | issue = 3 | pages = 223-8 | month = Mar | year = 2003 | doi = 10.1097/01.MP.0000056627.21128.74 | PMID = 12640102 }}</ref>
*Rare.
 
===Microscopic===
Features:<ref>URL: [http://www.breastpathology.info/Case_of_the_month/2007/COTM_0707%20discussion.html http://www.breastpathology.info/Case_of_the_month/2007/COTM_0707%20discussion.html]. Accessed on: 28 November 2010.</ref>
* Lymphocytic infiltrates - '''key feature''':
** Lobules.
** Perivascular.
* Enlarged stromal fibroblasts.
* Stromal collagen with keloid-like changes.
 
DDx:
*Diabetic mastopathy - if individual has diabetes.
*Primary [[lymphoma]] of the breast.
 
Images:
*[http://www.webpathology.com/image.asp?n=1&Case=655 Lymphocytic mastitis - low mag. (webpathology.com)].
*[http://www.webpathology.com/image.asp?case=655&n=2 Lymphocytic mastitis - high mag. (webpathology.com)].
 
===IHC===
*B cell predominant (CD20 > CD3).<ref name=pmid12640102/>
**B cells CD43 -ve.
 
===Molecular===
*Negative clonality studies.


==Microglandular adenosis==
==Microglandular adenosis==
Michael
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