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Gynecomastoid hyperplasia (view source)
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'''Gynecomastoid hyperplasia''', also '''gynecomastia''', is a benign [[breast pathology|pathology of the breast]] classically seen in young men. | |||
==General== | |||
*Benign enlargement of breasts in males. | |||
**Histologic changes may be seen in females.<ref name=stony03>URL: [http://www.hsc.stonybrook.edu/breast-atlas/XIII-03.htm http://www.hsc.stonybrook.edu/breast-atlas/XIII-03.htm]. Accessed on: 16 November 2011.</ref> | |||
May be seen in the context of: | |||
*[[Liver]] failure. | |||
*[[Klinefelter syndrome]]. | |||
*Testicular estrogen-producing [[germ cell tumour]]. | |||
==Microscopic== | |||
Features:<ref name=stony03>URL: [http://www.hsc.stonybrook.edu/breast-atlas/XIII-03.htm http://www.hsc.stonybrook.edu/breast-atlas/XIII-03.htm]. Accessed on: 16 November 2011.</ref> | |||
*Moderate hyperplasia. | |||
**Glands have more than 2 cell layers. | |||
*"Budding" - individual cells jut into the lumen - '''key feature'''. | |||
**Buds may be multicellular; however, narrower toward the centre of the lumen. | |||
*Stromal palor.<ref>URL: [http://radiology.uchc.edu/eAtlas/Breast/1693.htm http://radiology.uchc.edu/eAtlas/Breast/1693.htm]. Accessed on: 16 November 2011.</ref> | |||
DDx: | |||
*[[Micropapillary DCIS]] - buds not narrower toward the centre of the lumen. | |||
===Images=== | |||
<gallery> | |||
Image:Gynecomastoid_hyperplasia_-_intermed_mag.jpg | Gynecomastoid hyperplasia - intermed. mag. (WC/Nephron) | |||
Image:Gynecomastoid_hyperplasia_-_very_high_mag.jpg | Gynecomastoid hyperplasia - very high mag. (WC/Nephron) | |||
Image:Gynecomastoid_hyperplasia_-2-_intermed_mag.jpg | Gynecomastoid hyperplasia - 2 - intermed. mag. (WC/Nephron) | |||
</gallery> | |||
www: | |||
*[http://www.hsc.stonybrook.edu/breast-atlas/XIII-03.htm Gynecomastoid hyperplasia (stonybrook.edu)]. | |||
*[http://radiology.uchc.edu/eAtlas/Breast/1693.htm Gynecomastia (radiology.uchc.edu)]. | |||
==See also== | |||
*[[Breast pathology]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Breast pathology]] | |||