From Libre Pathology
|Diagnosis in short|
Gynecomastoid hyperplasia. H&E stain.
|LM||moderate hyperplasia - glands have more than 2 cell layers, "budding" (cells jut into the lumen, buds may be multicellular -- but narrower toward the centre of the lumen), stromal palor|
|LM DDx||Micropapillary DCIS|
|Associated Dx||Liver failure, Klinefelter syndrome, testicular estrogen-producing germ cell tumour|
|Signs||excessive breast tissue|
Gynecomastoid hyperplasia, also gynecomastia, is a benign pathology of the breast classically seen in young men.
- Benign enlargement of breasts in males.
- Histologic changes may be seen in females.
May be seen in the context of:
- Excessive breast tissue in males.
- Moderate hyperplasia.
- Glands have more than 2 cell layers.
- "Budding" - individual cells jut into the lumen - key feature.
- Buds may be multicellular; however, narrower toward the centre of the lumen.
- Stromal palor.
- Micropapillary DCIS - buds not narrower toward the centre of the lumen.
A. Breast Tissue (60 g), Right, Excision: - Benign breast tissue. B. Breast Tissue (70 g), Left, Excision: - Benign breast tissue.
- URL: http://www.hsc.stonybrook.edu/breast-atlas/XIII-03.htm. Accessed on: 16 November 2011.
- URL: http://radiology.uchc.edu/eAtlas/Breast/1693.htm. Accessed on: 16 November 2011.