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| *[[AKA]] ''papillary hyperplasia''. | | *[[AKA]] ''papillary hyperplasia''. |
| *[[AKA]] ''reactive papillary hyperplasia''. | | *[[AKA]] ''reactive papillary hyperplasia''. |
| ===General===
| | {{Main|Papillary urothelial hyperplasia}} |
| *Benign.
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| *Strong association with papillary neoplasms.
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| **On follow-up, in one study, >1/3 have a neoplasm; thus, follow-up is recommended.<ref name=pmid20438409>{{Cite journal | last1 = Readal | first1 = N. | last2 = Epstein | first2 = JI. | title = Papillary urothelial hyperplasia: relationship to urothelial neoplasms. | journal = Pathology | volume = 42 | issue = 4 | pages = 360-3 | month = Jun | year = 2010 | doi = 10.3109/00313021003767322 | PMID = 20438409 }}</ref>
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| ===Microscopic===
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| Features:<ref>URL: [http://pathology.jhu.edu/bladder/definitions.cfm http://pathology.jhu.edu/bladder/definitions.cfm]. Accessed on: 27 January 2014.</ref>
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| *Inflammation.
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| *Rare papillae
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| **Do not have a well-developed fibrovascular core.
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| *No urothelial cell atypia.
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| Image:
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| *[http://pathology.jhu.edu/bladder/image1.cfm?case_number=2&image_number=1 Papillary hyperplasia (jhu.edu)].
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| ===Sign out===
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| <pre>
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| URINARY BLADDER, BIOPSY:
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| - REACTIVE PAPILLARY HYPERPLASIA, SEE COMMENT.
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| - NO MUSCULARIS PROPRIA IDENTIFIED.
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| - CYSTITIS CYSTICA ET GLANDULARIS.
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| - NO EVIDENCE OF MALIGNANCY.
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| COMMENT:
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| The urothelial forms rare papillary structures; these are interpreted as reactive.
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| The urothelium stains as follow:
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| CK7: positive (patchy).
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| CK20: very rare superficial cells (normal).
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| Ki-67: rare, focally increased, negative in papillary structures (<10%).
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| p53: negative (weak focal <20%), very rare weak in rare papillary structures (<5%).
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| Follow-up is recommended.
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| </pre>
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|
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| =Benign urothelial lesions= | | =Benign urothelial lesions= |