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SKIN, BIOPSY: | SKIN, BIOPSY: | ||
<br>- ABSENCE OF NOTCH-3 IMMUNOSTAINING. | <br>- ABSENCE OF NOTCH-3 IMMUNOSTAINING. | ||
== Reactive gliosis == | |||
===Microscopic=== | |||
The section shows white matter and grey matter with regions of increased cellularity, consisting predominantly of regularily-spaced (glial) cells with bland-appearing, uniform, non-oviod nuclei. Glial cells, focally, have fine, eosinophilic, branching processes. A small subset of cells have moderate nuclear enlargement. | |||
Numerous axonal swellings are noted. There is no mitotic activity and no necrosis. No calcifications are identified. | |||
===Diagnosis=== | |||
BRAIN: | |||
<br>-REACTIVE GLIOSIS. |
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