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Difference between revisions of "Talk:Neuropathology"
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==CADASIL== | ==CADASIL== | ||
===Microscopic=== | ===Microscopic=== | ||
The | The biopsy, containing epidermis, dermis and subcutaneous tissue, is technically satisfactory. Immunostains utilizing a monoclonal antibody 1E4 (anti-Notch-3) at dilution 1:50 shows the absence of granular deposits in the walls of small arteries and veins in the dermis and subcutaneous tissue. Immunostains are strongly positive on positive control tissue from a patient known to have CADASIL. | ||
===Final diagnosis=== | ===Final diagnosis=== | ||
SKIN, BIOPSY: | SKIN, BIOPSY: | ||
<br> - | <br>- ABSENCE OF NOTCH-3 IMMUNOSTAINING. | ||