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| *[[AKA]] ''atrophy of the cervix''. | | *[[AKA]] ''atrophy of the cervix''. |
| *[[AKA]] ''cervix with atrophic changes''. | | *[[AKA]] ''cervix with atrophic changes''. |
| ===General===
| | {{Main|Uterine cervix with atrophic changes}} |
| *Common.
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| *Post-menupausal.
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| *Important to recognize and differentiate from [[HSIL]].
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| ===Microscopic===
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| Features:
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| *Cells smaller.
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| *Cytoplasm grey/blue.
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| *No "dancing"/"sparkling" chromatin.
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| *No mitoses.
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| DDx:
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| *[[HSIL]].
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| ====Images====
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| www:
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| *[http://nih.techriver.net/view.php?patientId=93 Atrophic cervix (nih.techriver.net)].
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| *[http://www.flickriver.com/photos/euthman/3884912676/ Atrophic cervix (flickriver.com/euthman)].
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| *[http://www.eurocytology.eu/static/eurocytology/image/mod1newa.jpg Atrophic changes in the vagina (eurocytology.eu)].<ref>URL: [http://www.eurocytology.eu/static/eurocytology/TUR/cervical/LP1ContentLcontC.html http://www.eurocytology.eu/static/eurocytology/TUR/cervical/LP1ContentLcontC.html]. Accessed on: 13 December 2013.</ref>
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| ===IHC===
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| *p16 -ve.
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| *Ki-67 rare basal cells.
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| ===Sign out===
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| <pre>
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| UTERINE CERVIX, BIOPSY:
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| - SQUAMOUS MUCOSA WITH ATROPHIC CHANGES.
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| - BENIGN ENDOCERVICAL EPITHELIUM.
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| - NEGATIVE FOR DYSPLASIA.
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| COMMENT:
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| A p16 immunostain is negative. A Ki-67 immunostain marks rare basal cells.
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| </pre>
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|
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|
| ==Radiation changes of the endocervical epithelium== | | ==Radiation changes of the endocervical epithelium== |