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#Identify possible endocervical lesions. | #Identify possible endocervical lesions. | ||
=Benign | =Benign= | ||
==Nabothian cyst== | ==Nabothian cyst== | ||
===General=== | ===General=== | ||
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A p16 immunostain is negative. A Ki-67 immunostain marks rare basal cells. | A p16 immunostain is negative. A Ki-67 immunostain marks rare basal cells. | ||
</pre> | </pre> | ||
==Radiation changes of the endocervical epithelium== | |||
===General=== | |||
*Uncommon. | |||
*Clinical history: radiation treatment for cervical carcinoma.<ref name=pmid2209348/> | |||
===Microscopic=== | |||
Features:<ref name=pmid2209348>{{Cite journal | last1 = Frierson | first1 = HF. | last2 = Covell | first2 = JL. | last3 = Andersen | first3 = WA. | title = Radiation changes in endocervical cells in brush specimens. | journal = Diagn Cytopathol | volume = 6 | issue = 4 | pages = 243-7 | month = | year = 1990 | doi = | PMID = 2209348 }}</ref> | |||
*Nuclear enlargement with a normal [[NC ratio]]. | |||
*+/-Coarse chromatin. | |||
*+/-Nucleoli. | |||
*+/-Multinucleation - very common. | |||
*Histiocytes - common. | |||
=Non-invasive= | =Non-invasive= |
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