Difference between revisions of "Non-malignant skin disease"

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Non-malignant skin disease (view source)

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→‎Cutaneous calcinosis
(→‎Mastocytosis: split-out)
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==Cutaneous calcinosis==
==Cutaneous calcinosis==
*[[AKA]] ''calcinosis cutis''.
*[[AKA]] ''calcinosis cutis''.
===General===
{{Main|Cutaneous calcinosis}}
*Benign in itself; underlying cause may not be benign.
*May be a [[scrotum|scrotal]] lesion - known as ''scrotal calcinosis''.<ref name=pmid20178701>{{Cite journal  | last1 = Dubey | first1 = S. | last2 = Sharma | first2 = R. | last3 = Maheshwari | first3 = V. | title = Scrotal calcinosis: idiopathic or dystrophic? | journal = Dermatol Online J | volume = 16 | issue = 2 | pages = 5 | month =  | year = 2010 | doi =  | PMID = 20178701 }}</ref>
 
Subtypes:<ref name=emed>URL: [http://emedicine.medscape.com/article/1103137-overview http://emedicine.medscape.com/article/1103137-overview]. Accessed on: 21 September 2011.</ref>
#Dystrophic - due to death of cells; may be related to a tumour.
#Metastatic - due to chronic renal failure; hyperkalemia; paraneoplastic phenomenon.
#Iatrogenic - post surgical.
#Idiopathic.
 
===Microscopic===
Features:
*Dermal calcification:
**Acellular purple blobs on [[H&E]].
***+/-Artefactual tearing of surrounding tissue due to processing (cutting).
***+/-Small artefactual lines ~1-2 micrometers due to processing (cutting).
***+/-Greyish rim of paucicellular material.
**Usu. well-circumscribed.
***May be surrounded by a palisading granuloma & [[giant cell]]s.
 
Images:
*[http://www.dermatopathonline.com/calcinosis%20cutis2.html Calcinosis cutis (dermatopathonline.com)].
 
===Sign out===
<pre>
SKIN AND SUBCUTANEOUS LESION, LEFT HIP, EXCISION:
- SUBCUTANEOUS CALCIFICATION SURROUNDED BY BENIGN FIBROUS TISSUE.
- DERMAL SCAR.
- NEGATIVE FOR MALIGNANCY.
</pre>
 
<pre>
SUBCUTANEOUS MASS, OVER BURSA OF ELBOW, EXCISION:
- CALCINOSIS CUTIS.
</pre>
 
====Micro====
The sections show subcutaneous calcifications surrounded by macrophages and giant cells. No nuclear atypia is apparent. The overlying skin is unremarkable.


==Dilated pore of Winer==
==Dilated pore of Winer==
Michael
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