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(→Cervical intraepithelial neoplasia: split-out) |
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Line 504: | Line 504: | ||
*CEA -ve/+ve. | *CEA -ve/+ve. | ||
*p16 -ve.{{fact}} | *p16 -ve.{{fact}} | ||
==Atrophy of the uterine cervix== | |||
*[[AKA]] ''cervical atrophy''. | |||
*[[AKA]] ''atrophy of the cervix''. | |||
*[[AKA]] ''cervix with atrophic changes''. | |||
===General=== | |||
*Common. | |||
*Post-menupausal. | |||
*Important to recognize and differentiate from [[HSIL]]. | |||
===Microscopic=== | |||
Features: | |||
*Cells smaller. | |||
*Cytoplasm grey/blue. | |||
*No "dancing"/"sparkling" chromatin. | |||
*No mitoses. | |||
DDx: | |||
*[[HSIL]]. | |||
===IHC=== | |||
*p16 -ve. | |||
*Ki-67 rare basal cells. | |||
===Sign out=== | |||
<pre> | |||
UTERINE CERVIX, BIOPSY: | |||
- SQUAMOUS MUCOSA WITH ATROPHIC CHANGES. | |||
- BENIGN ENDOCERVICAL EPITHELIUM. | |||
- NEGATIVE FOR DYSPLASIA. | |||
COMMENT: | |||
A p16 immunostain is negative. A Ki-67 immunostain marks rare basal cells. | |||
</pre> | |||
=Non-invasive= | =Non-invasive= |
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