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Line 917: | Line 917: | ||
- NO MICROORGANISMS APPARENT WITH H&E STAINING. | - NO MICROORGANISMS APPARENT WITH H&E STAINING. | ||
- NEGATIVE FOR MALIGNANCY. | - NEGATIVE FOR MALIGNANCY. | ||
</pre> | |||
==Toenail== | |||
===General=== | |||
*Relatively common. | |||
===Microscopic=== | |||
Features: | |||
*Nail plate - paucicellular, dense connective tissue. | |||
*Keratinized squamous epithelium. | |||
*+/-Cocci organisms. | |||
DDx: | |||
*[[Malignant melanoma]]. | |||
*Trauma. | |||
===Stains=== | |||
For pigmented lesion: | |||
*[[Prussian blue stain]] - trauma +ve, melanocytic lesion -ve. | |||
*[[Fontana-Masson stain]] - trauma -ve, melanocytic lesion usu. +ve. | |||
===Sign out=== | |||
====Pigmented nail==== | |||
<pre> | |||
PARTIAL NAIL PLATE, RIGHT THIRD TOE, SCISSOR EXCISION: | |||
- NAIL PLATE AND THIN LAYER OF KERATINIZED SQUAMOUS EPITHELIUM WITH | |||
PARAKERATOSIS AND FIBRIN. | |||
- NO APPARENT PIGMENT. | |||
- NO EVIDENCE OF MALIGNANCY. | |||
</pre> | |||
=====Micro===== | |||
The sections show a paucicellular nail plate, and a thin layer of squamous epithelium with | |||
keratinization and partial retention of the nuclei (parakeratosis). There is also a small | |||
amount of fibrin. No pigmentation is apparent with Prussian blue and Fontana-Masson | |||
staining. No melanocytes are apparent. No nuclear atypia is apparent. No mitotic activity | |||
is identified. No microorganisms are apparent. No significant inflammation is apparent. | |||
====Query infection===== | |||
<pre> | |||
GREAT TOENAIL, RIGHT, EXCISION: | |||
- NAIL PLATE AND THIN LAYER OF KERATINIZED SQUAMOUS EPITHELIUM. | |||
- SMALL CLUSTERS OF COCCI, FOCAL. | |||
- NO APPARENT FUNGAL ORGANISMS WITH PASF STAIN. | |||
- NO EVIDENCE OF MALIGNANCY. | |||
</pre> | </pre> | ||
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