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Edmondson-Steiner grading system:<ref name=pmid13160935>Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies. EDMONDSON HA, STEINER PE. Cancer. 1954 May;7(3):462-503. PMID 13160935.</ref><ref name=macsween5th>{{Ref MacSween|783}}</ref> | Edmondson-Steiner grading system:<ref name=pmid13160935>Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsies. EDMONDSON HA, STEINER PE. Cancer. 1954 May;7(3):462-503. PMID 13160935.</ref><ref name=macsween5th>{{Ref MacSween|783}}</ref> | ||
*Well-differentiated. | *Well-differentiated. | ||
**Some say "it cannot be diagnosed on biopsy,"<ref> | **Some say "it cannot be diagnosed on biopsy,"<ref>Pollet A. 28 May 2009.</ref> as it cannot be reliably differentiated from a regenerative nodule. | ||
*Moderately differentiated. | *Moderately differentiated. | ||
**Round, regular nuclei, some hyperchromatism, nucleoli present, increase NC ratio. | **Round, regular nuclei, some hyperchromatism, nucleoli present, increase NC ratio. |
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