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Difference between revisions of "Urothelium"
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→High grade papillary urothelial carcinoma: tweak
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*[[Low grade papillary urothelial carcinoma]]. | *[[Low grade papillary urothelial carcinoma]]. | ||
===IHC=== | |||
*Ki-67 >50% of tumour cells.<ref name=pmid23944616>{{Cite journal | last1 = Rajcani | first1 = J. | last2 = Kajo | first2 = K. | last3 = Adamkov | first3 = M. | last4 = Moravekova | first4 = E. | last5 = Lauko | first5 = L. | last6 = Felcanova | first6 = D. | last7 = Bencat | first7 = M. | title = Immunohistochemical characterization of urothelial carcinoma. | journal = Bratisl Lek Listy | volume = 114 | issue = 8 | pages = 431-8 | month = | year = 2013 | doi = | PMID = 23944616 }}</ref> | |||
**Low-grade UCC <25% of tumour cells positive. | |||
===Molecular=== | |||
Molecular changes:<ref name=pmid19468362>{{Cite journal | last1 = Ehdaie | first1 = B. | last2 = Theodorescu | first2 = D. | title = Molecular markers in transitional cell carcinoma of the bladder: New insights into mechanisms and prognosis. | journal = Indian J Urol | volume = 24 | issue = 1 | pages = 61-7 | month = Jan | year = 2008 | doi = 10.4103/0970-1591.38606 | PMID = 19468362 | PMC = 2684226}}</ref> | |||
*p53. | |||
*p21. | |||
*RB. | |||
*E-cadherin - decreased bad. | |||
*RhoGD12 - increased bad. | |||
*VEGF - increased bad. | |||
===Sign out=== | ===Sign out=== | ||