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Difference between revisions of "Malignant melanoma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Melanoma40x.JPG | |||
| Width = | |||
| Caption = Malignant melanoma. [[H&E stain]]. | |||
| Micro = melanocytic differentiation (e.g. pigment), abnormal architecture, lack of maturation, +/-nuclear atypia - esp. nucleoli, +/-upward scatter of melanocytes, +/-asymmetry of pigmentation | |||
| Subtypes = | |||
| LMDDx = [[dysplastic nevus]], [[Spitz nevus]], [[common nevus]] (nevoid melanoma), [[atypical fibroxanthoma]], (spindle cell) [[squamous cell carcinoma]], [[leiomyosarcoma]], poorly differentiated carcinoma | |||
| Stains = melanin | |||
| IHC = S-100, Melan A, HMB-45, mitf, tyrosinase | |||
| EM = melanosomes | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[skin]], others | |||
| Assdx = | |||
| Syndromes = familial melanoma | |||
| Signs = ABCDE = asymmetrical, border irregular, colour (black), diameter large, evolving (growing) | |||
| Symptoms = | |||
| Prevalence = common | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = | |||
}} | |||
'''Malignant melanoma''', also '''melanoma''', is an aggressive type of skin cancer that can be diagnostically challenging for pathologists. | '''Malignant melanoma''', also '''melanoma''', is an aggressive type of skin cancer that can be diagnostically challenging for pathologists. | ||